Results 41 to 50 of about 5,454,481 (202)

Age‐related differentiations of Th1/Th2 cytokines in newborn infants

Mediators of Inflammation, Volume 13, Issue 2, Page 89-92, 2004., 2004
OBJECTIVE: To evaluate age‐related differentiation of immune response in newborns by measuring serum concentrations of interleukin‐2 (IL‐2), interleukin‐4 (IL‐4) and interferon‐γ (IFN‐γ) during the perinatal period. Subjects and methods: Fifty‐seven healthy term neonates, their mothers and 25 healthy adults (controls) age‐matched to the mothers were ...
Efthimia Protonotariou, Ariadne Malamitsi-Puchner, Demetrios Rizos, Basiliki Papagianni, Evangelia Moira, Angeliki Sarandakou, Demetrios Botsis   +6 more
wiley   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Antibodies to Human Thymic Epithelium Form Part of the Murine Autoreactive Repertoire

Journal of Immunology Research, Volume 8, Issue 2, Page 75-93, 2001., 2001
Monoclonal antibody (mAb) MR6 recognises a 200 kDa glycoprotein, gp200‐MR6, which is expressed at high levels on the surface of human thymic cortical epithelium. In order to produce further mAbs against the gp200‐MR6 molecule, mice were immunised with purified human gp200‐MR6, hybridomas produced and supernatants screened for MR6‐like reactivity on ...
Jona Freysdottir, Mary A. Ritter
wiley   +1 more source

A Humanized Immunoenzyme with Enhanced Activity for Glucuronide Prodrug Activation in the Tumor Microenvironment

, 2016
Antibody-directed enzyme prodrug therapy (ADEPT) utilizing β-glucuronidase is a promising method to enhance the therapeutic index of cancer chemotherapy.
Yu-Lin Leu (2199214), Steve R. Roffler (75181), Zeljko M. Prijovich (461489), Hsin-Ell Wang (307175), Tian-Lu Cheng (563253), Bing-Mae Chen (461486), Kai-Chuan Chen (461492), Shih-Yen Wu (2199211)   +7 more
core   +1 more source

Spindle Cell Sarcoma of the Abdominal Aorta Following Endovascular Aneurysm Repair in a Kidney Transplant Recipient

Case Reports in Transplantation, Volume 2026, Issue 1, 2026.
A kidney transplant recipient developed spindle cell sarcoma within an abdominal aortic aneurysm following prior endovascular aneurysm repair (EVAR). The patient had undergone EVAR for abdominal aortic aneurysm before successful living‐donor kidney transplantation and maintained stable graft function under immunosuppressive therapy.
Kota Kakeshita, Teruhiko Imamura, Hidenori Yamazaki, Kanetsugu Nagao, Shigeyuki Yamashita, Shinya Kajiura, Naotaka Nishiyama, Noriko Okuno, Tsutomu Koike, Hiroshi Kitamura, Koichiro Kinugawa, Evaldo Favi   +11 more
wiley   +1 more source

Anti‐inflammatory response of IL‐4, IL‐10 and TGF‐β in patients with systemic inflammatory response syndrome

Mediators of Inflammation, Volume 9, Issue 3-4, Page 193-195, 2000., 2000
The systemic inflammatory response syndrome (SIRS) is an inflammatory process seen in association with a large number of clinical infective and noninfective conditions. The aim of this study was to investigate the role of anti‐inflammatory cytokines such as interleukin–4 (IL–4), interleukin–10 (IL–10), and transforming growth factor‐beta (TGF‐beta ...
Donato Torre, Roberto Tambini, Silvana Aristodemo, Giovanna Gavazzeni, Antonio Goglio, Carla Cantamessa, Agostino Pugliese, Gilberto Biondi   +7 more
wiley   +1 more source

Determination of the phytophthora infestans antigen with the use of an immunoenzyme amperometric sensor [PDF]

, 1999
It was proposed to diagnose the PhI potato disease, to assess the severity of the disease in plants, and to timely determine the presence of the PhI antigen in the test samples using an immunoenzyme sensor.
Khaldeeva E., Glushko N., Kutyreva M., Medyantseva E., Budnikov G.   +4 more
core  

Rotavirus infection in a tertiary hospital: laboratory diagnosis and impact of immunization on pediatric hospitalization

Brazilian Journal of Infectious Diseases
BACKGROUND AND OBJECTIVES: Rotavirus (RV) is the main etiological agent of diarrhea in childhood; its laboratory diagnosis is crucial to guide the clinical management and prevention of its spread.
Luciane Aparecida Pereira, Sonia Mara Raboni, Meri B Nogueira, Luine R Vidal, Sergio Monteiro de Almeida, Maria C Debur, Cristina Cruz   +6 more
doaj   +1 more source

Rotavirus infection in a tertiary hospital: laboratory diagnosis and impact of immunization on pediatric hospitalization

Brazilian Journal of Infectious Diseases, 2011
Background and objectives: Rotavirus (RV) is the main etiological agent of diarrhea in childhood; its laboratory diagnosis is crucial to guide the clinical management and prevention of its spread.
Luciane Aparecida Pereira, M.Sc., Sonia Mara Raboni, Ph.D., Meri B. Nogueira, Ph.D., Luine R. Vidal, Ph.D., Sergio Monteiro de Almeida, M.Sc., Maria C. Debur, M.Sc., Cristina Cruz, M.Sc.   +6 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, Volume 10, Issue S1, Page S112-S135, August 2025.
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source