Results 1 to 10 of about 14,737,518 (270)

Development and Validation of a Rapid Screening Test for HTLV-I IgG Antibodies [PDF]

Viruses, 2022
Initial diagnosis of human T cell lymphotropic virus (HTLV) infections is mainly based by detecting antibodies in plasma or serum using laboratory-based methods.
Bobby Brooke Herrera, Rafaela Mayoral, Carlos Brites   +2 more
doaj   +2 more sources

A novel high-performance rapid screening test for the detection of total HTLV-I and HTLV-II antibodies in HTLV-I/II infected patients [PDF]

BMC Infectious Diseases
Rapid diagnosis of human T-cell lymphotropic virus (HTLV) type-I and -II infections are essential for timely and cost-effective disease interventions.
Lay Sin Teoh, Vincent Guiraud, Haris Ong, Yang Du, Zhihai Zhao, Agnès Gautheret-Dejean, Na Xu   +6 more
doaj   +2 more sources

The Prevalence and Significance of HTLV-I/II Seroindeterminate Western Blot Patterns

Viruses, 2011
Human T-lymphotropic virus type I (HTLV-I) infects an estimated 15–20 million persons worldwide. A number of diseases have been associated with the virus including adult T-cell leukemia (ATL), HTLV-associated myelopathy/tropical spastic paraparesis (HAM ...
Yoshimi Akahata, Anna Abrams, Steven Jacobson   +2 more
doaj   +2 more sources

Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma. [PDF]

Cancer Cell, 2018
Adult T cell leukemia/lymphoma (ATLL) is a frequently incurable disease associated with the human lymphotropic virus type I (HTLV-I). RNAi screening of ATLL lines revealed that their proliferation depends on BATF3 and IRF4, which cooperatively drive ATLL-
Nakagawa M, Shaffer AL, Ceribelli M, Zhang M, Wright G, Huang DW, Xiao W, Powell J, Petrus MN, Yang Y, Phelan JD, Kohlhammer H, Dubois SP, Yoo HM, Bachy E, Webster DE, Yang Y, Xu W, Yu X, Zhao H, Bryant BR, Shimono J, Ishio T, Maeda M, Green PL, Waldmann TA, Staudt LM.   +26 more
europepmc   +2 more sources

Neurological Signs and Symptoms in Human T-Lymphotropic Viruses 1 and 2 Infected Patients Living in the Amazon Region, Northern Brazil [PDF]

Viruses
HTLV-1 and HTLV-2 infections are associated with various neurological manifestations, particularly HTLV-1-associated myelopathy (HAM). This descriptive, cross-sectional observational study aimed to investigate and analyze the neurological manifestations ...
Giovani Camelo do Nascimento, Lucas Thiago Ferreira Monteiro, Hemengella Karyne Alves Oliveira, Márcio Yutaka Tsukimata, Bianca Lumi Inomata da Silva, Aline Cecy Rocha Lima, Rodrigo Borges de Oliveira, Gabriel dos Santos Pereira Neto, Eduardo Leitão Maia, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Izaura Maria Vieira Cayres Vallinoto   +11 more
doaj   +2 more sources

HTLV-1/2 Infection in Blood Donors from a Non-Endemic Area (Catalonia, Spain) between 2008 and 2017: A 10-Year Experience

Viruses, 2022
Human T-cell lymphotropic virus type 1 and 2 (HTLV-1/2) screening is not mandatory in Spanish blood banks. In Catalonia, selective screening was introduced in 2008, followed by universal screening in 2011.
Maria Piron, Fernando Salvador, Estrella Caballero, Adrián Sánchez-Montalvá, Marta Bes, Natàlia Casamitjana, Lluís Puig, Israel Molina, Silvia Sauleda   +8 more
doaj   +1 more source

Understanding HTLV-I Protease [PDF]

Chemistry & Biology, 2003
AbstractHuman T cell leukemia virus type I (HTLV-I) is a human retrovirus that has been clinically associated with adult T cell leukemia/lymphoma, and it has been designated as a dangerous emerging pathogen by the Centers for Disease Control. Like other retroviruses, proteolytic processing of specific sites in polyprotein precursors by a retroviral ...
Shuker, Suzanne Beckham, Mariani, Victoria L., Herger, Bryan E., Dennison, Kelly J.   +3 more
openaire   +2 more sources

Upregulation of Neuropilin-1 Inhibits HTLV-1 Infection

Pathogens, 2023
Infection with human T-cell leukemia virus type 1 (HTLV-1) can produce a spectrum of pathological effects ranging from inflammatory disorders to leukemia. In vivo, HTLV-1 predominantly infects CD4+ T-cells.
Wesley Kendle, Kimson Hoang, Erica Korleski, Amanda R. Panfil, Nicholas Polakowski, Isabelle Lemasson   +5 more
doaj   +1 more source

Respiratory and Urinary Tract Infections, Arthritis, and Asthma Associated with HTLV-I and HTLV-II Infection

Emerging Infectious Diseases, 2004
Human T-lymphotropic virus types I and II (HTLV-I and -II) cause myelopathy; HTLV-I, but not HTLV-II, causes adult T-cell leukemia. Whether HTLV-II is associated with other diseases is unknown.
Edward L. Murphy, Baoguang Wang, Ronald A. Sacher, Joy Fridey, James W. Smith, Catharie C. Nass, Bruce Newman, Helen E. Ownby, George Garratty, Sheila T. Hutching, George B. Schreiber   +10 more
doaj   +1 more source

Clinical and immunological consequences of human T cell leukemia virus type-I and Schistosoma mansoni co-infection

Memorias do Instituto Oswaldo Cruz, 2004
Human T cell leukemia virus type-I (HTLV-I) infection is associated with spontaneous T cell activation and uncontrolled lymphocyte proliferation. An exacerbated type-1 immune response with production of pro-inflammatory cytokines (interferon-gamma and ...
Silvane Braga Santos, Aurélia Fonseca Porto, André Luiz Muniz, Amélia Ribeiro de Jesus, Edgar M Carvalho   +4 more
doaj   +1 more source