Results 31 to 40 of about 14,737,518 (270)

Exacerbated inflammatory cellular immune response characteristics of HAM/TSP is observed in a large proportion of HTLV-I asymptomatic carriers [PDF]

, 2004
Background A small fraction of Human T cell Leukemia Virus type-1 (HTLV-I) infected subjects develop a severe form of myelopathy. It has been established that patients with HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) show an ...
Silvane Braga Santos, Aurélia Fonseca Porto, André Luiz Muniz, Amélia Ribeiro de Jesus, Elza Magalhães, Ailton Melo, Walderez O Dutra, Kenneth J Gollob, Edgar M Carvalho, B Galvao-Castro, ED Moreira Jr, T Uchiyama, BJ Poiesz, A Gessain, M Osame, H Prince, R Kubota, N Nishimoto, M Osame, S Jacobson, S Jacobson, GP Taylor, S Izumo, JF Kurtzke, A Kramer, M Nagai, E Hanon, N Azimi, R Kubota, M Nagai, EM Carvalho, F Umehara, WE Biddison, JH Richardson, M Popovic, JA Sakai, M Azuma, MP Weekes, JF Giguere, WO Dutra   +39 more
core   +2 more sources

A Potential of an Anti-HTLV-I gp46 Neutralizing Monoclonal Antibody (LAT-27) for Passive Immunization against Both Horizontal and Mother-to-Child Vertical Infection with Human T Cell Leukemia Virus Type-I

Viruses, 2016
Although the number of human T-cell leukemia virus type-I (HTLV-I)-infected individuals in the world has been estimated at over 10 million, no prophylaxis vaccines against HTLV-I infection are available.
Hideki Fujii, Mamoru Shimizu, Takuya Miyagi, Marie Kunihiro, Reiko Tanaka, Yoshiaki Takahashi, Yuetsu Tanaka   +6 more
doaj   +1 more source

HTLV-I screening in Britain [PDF]

BMJ, 1995
The human T cell leukaemia/lymphoma virus type I (HTLV-I) was isolated nearly 17 years ago from a patient who had what is now called adult T cell leukaemia/lymphoma. This aggressive condition responds poorly to chemotherapy, with a median survival of only a few months.1 HTLV-I is also unequivocally linked with tropical spastic paraparesis, a ...
A, Pagliuca, R, Pawson, G J, Mufti
openaire   +2 more sources

HTLV-I Tax Increases Genetic Instability by Inducing DNA Double Strand Breaks during DNA Replication and Switching Repair to NHEJ

PLoS ONE, 2012
Background Appropriate responses to damaged DNA are indispensible for preserving genome stability and preventing cancer. Tumor viruses often target DNA repair machinery to achieve transformation.
H. Baydoun, X. Bai, Shary Shelton, C. Nicot   +3 more
semanticscholar   +1 more source

Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing [PDF]

, 2007
BACKGROUND: HTLV-I infected CD4+ T-cells lines usually progress towards a CD3- or CD3low phenotype. In this paper, we studied expression, kinetics, chromatin remodeling of the CD3 gene at different time-points post HTLV-I infection. RESULTS: The onset of
Haidar Akl, Bassam Badran, Gratiela Dobirta, Germain Manfouo-Foutsop, Maria Moschitta, Makram Merimi, Arsène Burny, Philippe Martiat, Karen E Willard-Gallo   +8 more
core   +1 more source

The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication [PDF]

, 2006
Emerging evidence suggests that supernumerary centrosomes drive genome instability and oncogenesis. Human T-cell leukaemia virus type I (HTLV-I) is etiologically associated with adult T-cell leukaemia (ATL).
A Gromley, A Haoudi, A Khodjakov, A Kramer, AB D'Assoro, ACS Chun, AM Fry, C Wong, C Zou, D-Y Jin, D-Y Jin, Dong-Yan Jin, DY Jin, EA Nigg, GA Pihan, J Yang, J Yang, JM Peloponese, K-T Chin, K-T Jeang, KR Lacey, Kuan-Teh Jeang, M Forgues, M Matsuoka, M Okuda, ML Gatza, OJ Semmes, P Meraldi, PJ Paddison, RC Gallo, S Bahe, S Doxsey, S Duensing, Shing-Fai Chan, Y Matsumoto, Y-P Ching, Yick-Pang Ching, YP Ching, YP Ching, YY Ou   +39 more
core   +1 more source

Risk Factors for Human T Cell Lymphotropic Virus Type I among Injecting Drug Users in Northeast Brazil: Possibly Greater Efficiency of Male to Female Transmission

Memorias do Instituto Oswaldo Cruz, 1999
It was observed in the city of Salvador, State of Bahia, the highest seroprevalence of human T cell lymphotropic virus type 1 (HTLV-I) infection in Brazil as demonstrated by national wide blood bank surveys.
Inês Dourado, Tarcísio Andrade, Catherine L Carpenter, Bernardo Galvão-Castro   +3 more
doaj   +1 more source

Loss of correlation between HIV viral load and CD4+ T-cell counts in HIV/HTLV-1 co-infection in treatment naive Mozambican patients [PDF]

, 2009
Seven hundred and four HIV-1/2-positive, antiretroviral therapy (ART) naïve patients were screened for HTLV-1 infection. Antibodies to HTLV-1 were found in 32/704 (4.5%) of the patients.
Augusto, O, Bhatt, N B, Bila, D, Di Mattei, P, Garsia, R, Gudo, E S, Jani, I V, Semá, C   +7 more
core   +2 more sources

Endemic HTLV in Japan and South America with special reference to mongoloid dispersal from Asia to the Andes

Estudios Atacameños, 1998
Se ha estimado que existe 1,2 millones de portadores del virus humano de la leucemia T tipo I (HTLV I) en todo el Japón, donde la incidencia de leucemia a linfocitos T del adulto es la más alta del mundo.
Kazuo Tajima, Shunro Sonoda, Luis Cartier, Vladimir Zaninovic, Lautaro Núñez Atencio, Luis Hurtado Gómez, Sonia Guillén, José Dipierri, Toshiro Takezaki, Toshinobu Fujiyoshi, Satoshi Horai   +10 more
doaj   +1 more source

Interactions between inflammatory gene polymorphisms and HTLV-I infection for total death, incidence of cancer, and atherosclerosis-related diseases among the Japanese population

Journal of Epidemiology, 2017
Background: An increased risk of total death owing to human T-lymphotropic virus type-I (HTLV-I) infection has been reported. However, its etiology and protective factors are unclear.
Tara Sefanya Kairupan
doaj   +1 more source