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Understanding HTLV-I Protease [PDF]
AbstractHuman T cell leukemia virus type I (HTLV-I) is a human retrovirus that has been clinically associated with adult T cell leukemia/lymphoma, and it has been designated as a dangerous emerging pathogen by the Centers for Disease Control. Like other retroviruses, proteolytic processing of specific sites in polyprotein precursors by a retroviral ...
Shuker, Suzanne Beckham +3 more
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HTLV-I screening in Britain [PDF]
The human T cell leukaemia/lymphoma virus type I (HTLV-I) was isolated nearly 17 years ago from a patient who had what is now called adult T cell leukaemia/lymphoma. This aggressive condition responds poorly to chemotherapy, with a median survival of only a few months.1 HTLV-I is also unequivocally linked with tropical spastic paraparesis, a ...
A, Pagliuca, R, Pawson, G J, Mufti
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Testing problems in diagnosing human T-lymphotropic virus (HTLV) infection, mostly HTLV-II, have been documented in HIV/AIDS patients. Since December 1998, the Immunology Department of Instituto Adolfo Lutz (IAL) offers HTLV-I/II serology to Public ...
Fabrício Jacob +3 more
doaj +1 more source
Serum- and/or- cerebrospinal fluid (CSF) samples obtained from 190 patients suffering from chronic, progressive neurological disease were screened for the presence of human T-cell lymphotropic viruses type I (HTLV-I) and type II (HTLV-II) antibodies over
Olinda Macêdo +5 more
doaj +1 more source
Background. Human T-cell lymphotropic virus type 1 (HTLV-1) is responsible for tropical spastic paraparesis and HTLV-1-associated leukemia/lymphoma. The infection is endemic in some areas of Peru, but its prevalence in the Peruvian Amazon is not well ...
José-Manuel Ramos-Rincón +10 more
doaj +1 more source
Laboratory diagnosis of human T-lymphotropic viruses (HTLV) 1 and 2 infection is performed by serological screening and further confirmation with serological or molecular assays.
Yago Gomes +8 more
doaj +1 more source
Although the number of human T-cell leukemia virus type-I (HTLV-I)-infected individuals in the world has been estimated at over 10 million, no prophylaxis vaccines against HTLV-I infection are available.
Hideki Fujii +6 more
doaj +1 more source
Background Human T-cell leukemia virus type I (HTLV-I) is associated with pulmonary diseases, characterized by bronchoalveolar lymphocytosis, which correlates with HTLV-I proviral DNA in carriers.
Yara Satomi +10 more
doaj +1 more source
The Prevalence and Significance of HTLV-I/II Seroindeterminate Western Blot Patterns
Human T-lymphotropic virus type I (HTLV-I) infects an estimated 15–20 million persons worldwide. A number of diseases have been associated with the virus including adult T-cell leukemia (ATL), HTLV-associated myelopathy/tropical spastic paraparesis (HAM ...
Yoshimi Akahata +2 more
doaj +1 more source
It was observed in the city of Salvador, State of Bahia, the highest seroprevalence of human T cell lymphotropic virus type 1 (HTLV-I) infection in Brazil as demonstrated by national wide blood bank surveys.
Inês Dourado +3 more
doaj +1 more source

