Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) [PDF]
Retrovirology, 2008 Background HTLV-I is the causal agent of adult T cell leukemia (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Biomarkers are needed to diagnose and/or predict patients who are at risk for HAM/TSP or ATLL.
Mahieux Renaud +10 more
doaj +4 more sources
Enhanced HIV-1 Neutralizing Antibody Breadth in HTLV-2 Co-Infected Individuals: Influence of Antiretroviral Regimen and B Cell Subset Distribution [PDF]
VaccinesBackground/Objectives: This study aimed to explore how HTLV-2 infection affects the production of broadly neutralizing antibodies (bNAbs) in persons with HIV-1 (PWH) and to assess the impact of boosted protease inhibitors (PIs).
Eloisa Yuste +9 more
doaj +2 more sources
Development and Validation of a Rapid Screening Test for HTLV-I IgG Antibodies
Viruses, 2022 Initial diagnosis of human T cell lymphotropic virus (HTLV) infections is mainly based by detecting antibodies in plasma or serum using laboratory-based methods.
Bobby Brooke Herrera +2 more
doaj +1 more source
The tax-inducible actin-bundling protein fascin is crucial for release and cell-to-cell transmission of human T-cell leukemia virus type 1 (HTLV-1) [PDF]
, 2016 The delta-retrovirus Human T-cell leukemia virus type 1 (HTLV-1) preferentially infects CD4(+) T-cells via cell-to-cell transmission. Viruses are transmitted by polarized budding and by transfer of viral biofilms at the virological synapse (VS ...
Gettemans, Jan +6 more
core +23 more sources
The Lancet Regional Health. Americas, 2022 Summary: Background: Brazil is a country endemic for human T-lymphotropic virus 1 and 2 (HTLV-1 and HTLV-2), systemic mycoses such as paracoccidioidomycosis (PCM) and histoplasmosis (HP), and aspergillosis (AP). The prevalence of HTLV-1/-2 infections in
Adele Caterino-de-Araujo +3 more
doaj +1 more source
Chemiluminescence Immunoassay to Detect Anti‐HTLV‐I Antibodies [PDF]
Japanese Journal of Cancer Research, 1993 A fully automated chemiluminescence immunoassay was developed for the detection of antibodies to HTLV‐I. We used partially purified viral antigens coated on small polystyrene beads together with acridinium ester‐labeled anti‐human immunoglobulin G mouse immunoglobulin G in this method.
Kamihira, Shimeru +5 more
openaire +2 more sources
Human T-lymphotropic virus and transfusion safety. Does one size fit all? [PDF]
, 2015 Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable.
Catalano, Liviana +7 more
core +1 more source
Pathogens, 2021 Background. Human T-cell lymphotropic virus type 1 (HTLV-1) is responsible for tropical spastic paraparesis and HTLV-1-associated leukemia/lymphoma. The infection is endemic in some areas of Peru, but its prevalence in the Peruvian Amazon is not well ...
José-Manuel Ramos-Rincón +10 more
doaj +1 more source
Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]
, 2016 Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra +10 more
core +2 more sources
Revista do Instituto de Medicina Tropical de São Paulo, 2004 Serum- and/or- cerebrospinal fluid (CSF) samples obtained from 190 patients suffering from chronic, progressive neurological disease were screened for the presence of human T-cell lymphotropic viruses type I (HTLV-I) and type II (HTLV-II) antibodies over
Olinda Macêdo +5 more
doaj +1 more source