Results 201 to 210 of about 238,930 (305)

Immunogenicity and safety of co-administered <i>Escherichia coli</i>-produced bivalent HPV-16/18 vaccine and hepatitis E vaccine. [PDF]

Front Immunol
Yan R, Cen M, Zhou Y, Ma L, Zhou X, He H, Qi X, Tang X, Liang H, Chen Y, Qi J, Yang S.   +11 more
europepmc   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Author Correction: Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension

Scientific Reports
Shan-Shan Zhang, Lance Larrabee, Andrew H. Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C. Hartman, Abby Whitnall, Joseph Mason, Nicholas P. Barton, Audrey Y. Chu, Jonathan M. Davitte, Adam J. Csakai, Caitlin Vestal Tibbetts, Audrey E. Tolbert, Heather O’Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P. Mayer, Patrick Koenig, Davide Foletti, Steven J. Pitts, Christine G. Schnackenberg   +29 more
doaj   +1 more source

Summary of Research: Immunogenicity of Dupilumab in Adult and Pediatric Patients with Atopic Dermatitis. [PDF]

Dermatol Ther (Heidelb)
Kosloski MP, Lai CH, Partridge MA, Kanamaluru V, Bansal A, Shumel B, Ardeleanu M, Yan H, Xu C, Marco AR, Xiao J, Khokhar FA, Gherardi G, Babilonia E, Akinlade B, Torri A, Davis JD.   +16 more
europepmc   +1 more source

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

Advanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin, Hongru Wang, Yi Yang, Yuhang Xie, Yuan Zhang, Zhiye Du, Yi Huang, Wei Guo, Yang Li, Shidong Wang   +9 more
wiley   +1 more source

Computational identification of conserved dengue virus envelope protein epitopes for vaccine design and immunodiagnostic platform. [PDF]

Sci Rep
da Silva MK, Fulco UL, Alqahtani T, Sindi ER, Oliveira JIN, Zerihun YA, Zaki MEA, Akter S.   +7 more
europepmc   +1 more source

Genetic Code Expanded T Cell for Controllable Immunotherapy

Advanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang, Yingao Gao, Yeyu Su, Yong Wang, Tao Liu   +4 more
wiley   +1 more source

Safety and immunogenicity of 4CMenB and MenACWY-CRM meningococcal vaccines when administered concomitantly in healthy adolescents: A phase 3b, randomized, observer-blind study. [PDF]

Hum Vaccin Immunother
Hoberman A, Atwi J, Silas P, Prato R, Bosis S, Martin JM, Lechevin I, Possidente M, Manzella S, Moraschini L, Lattanzi M, Keshavan P.   +11 more
europepmc   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

Advanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang, Yiyuan Kang, Shulin Lai, Chunyi Wang, Guixin He, Kehui Jian, Suhan Yin, Xiner Tan, Xinru Zhou, Wenjing Liu, Fujian Zhao, Jia Liu, Longquan Shao   +12 more
wiley   +1 more source

SPAID: a comprehensive database for disease-specific autoantigens in autoimmune disorders. [PDF]

Adv Biotechnol (Singap)
Deng S, Wei F, Pang Y, Zhang L, Zhi S, Chen T, Zuo Z, Ren J, Xie Y, Luo X.   +9 more
europepmc   +1 more source