Results 231 to 240 of about 666,636 (307)

Rotavirus-Specific IgA and IgG Patterns During the First 2 Years of Life in the PREVAIL Birth Cohort. [PDF]

J Infect Dis
Baker JM, Mijatovic-Rustempasic S, Casey-Moore MC, White B, Mattison CP, Burke RM, Conrey SC, Morrow AL, Payne DC, Gautam R, Parashar UD, Tate JE, Staat MA, McNeal MM.   +13 more
europepmc   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Paraplegia Caused by IgG4-Related Hypertrophic Pachymeningitis With an Elevated Cerebrospinal Fluid Immunoglobulin G4 Concentration. [PDF]

Cureus
Doyama H, Matsumoto Y, Kurosaka A, Kobayashi M, Yamaguchi K.   +4 more
europepmc   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

<i>Streptococcus pneumoniae</i> Cerebellar Abscess in a Child With Specific Polysaccharide Antibody Deficiency: A Case Report. [PDF]

Case Rep Pediatr
Folga BA, Bronson AS, Whorf D, Rabbat J, Immergluck L.   +4 more
europepmc   +1 more source

Coordination‐Tuned Iridium Single‐Atom Nanozymes Boost Multienzyme Activity for Colorimetric Sensing

Advanced Science, EarlyView.
Breaking the coordination symmetry of Ir single‐atom sites through asymmetric Ir–N3S1 engineering tailors interfacial electron transfer, oxygen activation, and multienzyme‐like catalytic pathways. Operando spectroscopy and theoretical modeling uncover the atomic‐level origin of activity enhancement, providing a strategy for designing multifunctional ...
Tao Li, Xinyu Zhang, Jiashan Xia, Mengyu Wu, Cong Liu, Yapei Sun, Wanjiang Zhao, Min Qian, Wei Wang, Weixia Duan, Shangcheng Xu   +10 more
wiley   +1 more source

Association between prognostic nutritional index and complications in children with immunoglobulin A vasculitis. [PDF]

Front Nutr
Xiong X, Liu Z, Li H, Zhou Y, Yu L.
europepmc   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Pancytopenia as the Initial Presentation of Celiac Disease. [PDF]

ACG Case Rep J
Saravanamuthu PK, Das AK.
europepmc   +1 more source