Results 71 to 80 of about 114,676,913 (192)

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Intra-Alveolar Haemorrhage Complicating IgA Vasculitis: A Case Report, Literature Review and Discussion of Treatment

European Journal of Case Reports in Internal Medicine, 2019
Introduction: Immunoglobulin A vasculitis (IgAV) is a small-vessel vasculitis with IgA-dominant immune deposits. IgAV frequently involves the skin, gastrointestinal tract, joints and kidneys. In contrast to other types of small-vessel vasculitis, IgAV is
Benjamin Savoye, Gwenola Maigne, Evangeline Pillebout, Gaetane Planchard, Maxime Faisant, Achille Aouba, Alexandra Audemard   +6 more
doaj   +1 more source

Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy

This case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments.
Alencar, Alvaro J, Cohen, Jonathan J, Maderal, Andrea D, Warp, Peyton V, Desai, Karishma R   +4 more
core   +1 more source

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
Matthew Buckland (589995), Lorena Lorenzo (589997), Matthew Buckland, Dempster, J, Duraisingham Sai S., Longhurst Hilary J., Matthew Buckl, Sai S. Duraisingham, Sofia Grigoriadou (589998), Sai S Duraisingham, Hilary J Longhurst, John Dempster, Dempster John, Grigoriadou Sofia, Duraisingham, SS, Lorenzo, L, Buckland Matthew, Grigoriadou, S, Sofia Grigoriadou, Lorenzo Lorena, Sai S. Duraisingham (589994), Buckland, M, Longhurst, HJ, Lorena Lorenzo, John Dempster (589996), Buckland, MS, Hilary J. Longhurst (589999), Hilary J. Longhurst   +27 more
core   +2 more sources

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann, T. Mazza, S. Menzinger, G. Kaya, S. Bogiatzi, S. Vandenberghe‐Dürr, M. Blanchard, J. Stirnemann   +7 more
wiley   +1 more source

Adult onset of Immunoglobulin A vasculitis : A case report [PDF]

, 2019
Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, primarily occurs during childhood between the ages of 3 and 15 years and is the most common form of systemic vasculitis in children ; its occurrence in adults has been rarely
ヤマダ, ヒロツグ, Soeki, Takeshi, Wakatsuki, Tetsuzo, ソエキ, タケシ, サタ, マサタカ, エンドウ, イツロウ, ソガ, トモヒロ, 230, 197, ワカツキ, テツゾウ, 川人, 伸次, 231, 398, 曽我, 朋宏, フクダ, ダイジュ, Yamamoto, Yousuke, Kawahito, Shinji, 60303/profile-ja.html, 178255/profile-ja.html, 20592538, 伊勢, 孝之, 佐田, 政隆, Hida, Tetsuya, クスノセ, ケンヤ, 30403736, ヤマグチ, コウジ, ヤギ, シュウスケ, Yamaguchi, Koji, Murakami, Taichi, ヤマモト, ヨウスケ, イセ, タカユキ, 40637568, 80345214, 60284296, Yagi, Shusuke, 564, 山田, 博胤, 60393211, 400, 90621649, Sata, Masataka, ムラカミ, タイチ, 204912/profile-ja.html, 遠藤, 逸朗, 40380084, 00507650, 緋田, 哲也, Kusunose, Kenya, 173932/profile-ja.html, カワヒト, シンジ, Soga, Tomohiro, 90531377, 1159, 村上, 太一, 413, 山口, 浩司, 121162/profile-ja.html, Endo, Itsuro, 若槻, 哲三, 145663/profile-ja.html, 10432759, 240424/profile-ja.html, 70507649, 123698/profile-ja.html, 183, 145741/profile-ja.html, 340, 福田, 大受, 八木, 秀介, 540, 1644, ヒダ, テツヤ, 楠瀬, 賢也, Ise, Takayuki, 309, 添木, 武, Yamada, Hirotsugu, Fukuda, Daiju   +77 more
core  

Kawasaki disease in a infant

Revista de la Facultad de Medicina Humana, 2018
Kawasaki disease is an acute febrile illness of childhood characterized by vasculitis of the middle-sized, extraparenchymal arteries with a predilection for the coronary arteries.
Diana Cotrina Malca, Jorge Gálvez-Vallenas, Lucy E. Correa-López, Consuelo Luna-Muñoz   +3 more
doaj   +1 more source

The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]

, 2000
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core   +1 more source