Results 91 to 100 of about 161,876 (218)

Clinical characteristics of IgG4-related disease patients with different serum IgG4 levels: A single-center retrospective study

Journal of International Medical Research
Objective Immunoglobulin G4-related disease is a rare autoimmune disorder, and serum immunoglobulin G4 (IgG4) levels vary among patients. This study aimed to systematically compare the clinical features of patients with immunoglobulin G4-related disease ...
Dong-Ge Han, Lei Long, Qin-Xue Pu, Lu-Gao Tian, Wei Liu   +4 more
doaj   +1 more source

Immunoglobulin G4-Related Myocarditis with Eosinophilic Infiltration: A Case Report

, 2023
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fibroinflammatory disorder that can involve any organ system; however, myocarditis is extremely rare. A 52-year-old male with dyspnea and chest discomfort underwent cardiac MRI that revealed edema
Kye Taek Ahn, Hyeyoung Kwon, Hyun Woo, Song Soo Kim, Seon Ah Jin   +4 more
core   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes

, 2023
Mature B cells notably diversify immunoglobulin (Ig) production through class switch recombination (CSR), allowing the junction of distant “switch” (S) regions.
Brice Laffleur, Cogné, Michel, Laffleur, Brice, Ophélie Dézé, Michel Cogné, Deze, Ophelie   +5 more
core   +1 more source

Immunoglobulin G4-aortitis [PDF]

Rheumatology, 2019
John, Serelis, Fotini N, Skopouli, Christina, Ioakimidou, Haralampos M, Moutsopoulos   +3 more
openaire   +2 more sources

Solitary Indeterminate Cell Histiocytosis Presenting as a Reddish Nodule on the Abdomen of a 4‐Year‐Old Boy: Clinicopathologic Correlation and Electron Microscopy Findings

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Indeterminate cell histiocytosis (ICH) is a clonal proliferative disorder of mononuclear phagocyte cells that shows features of both dendritic and histiocytic cells. Only around 100 cases of ICH were reported, and among them, only 24% of reported cases involve pediatric patients, with a mean age at diagnosis of 50 years.
Seung‐Soo Lee, Seok‐Jong Lee, Weon Ju Lee, Dae‐Lyong Ha   +3 more
wiley   +1 more source

Immunoglobulin G4–related disease in Hong Kong: clinical features, treatment practices, and its association with multisystem disease [PDF]

, 2017
Introduction: Immunoglobulin G4–related disease remains an under-recognised and evolving disease. Local data are sparse and previous publications have been limited to individual case reports or case series only.
Lau, LL, Tsang, RKY, Li, PH, Ko, KL, Cheung, TT, Leung, WK, Ho, CTK, Lau, WCS   +7 more
core   +1 more source

Sensitization profiles in patients with wheat‐dependent exercise‐induced anaphylaxis: practical aspects for allergy workup

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Wheat‐dependent exercise‐induced anaphylaxis (WDEIA) occurs after ingestion of wheat/gluten in the presence of various cofactors. Here, we characterized the sensitization spectrum to various wheat flours, as revealed by skin prick test (SPT) and specific IgE (sIgE) against wheat flour, gluten, and various wheat components.
Enna M. Schwarze, Carolin C. Albers, Randolf Brehler, Mathias Sulk   +3 more
wiley   +1 more source