Results 151 to 160 of about 130,645 (352)

A case of amyloid goitre in heavy chain amyloidosis: diagnostic challenges and clinical implications

open access: yesEuropean Journal of Case Reports in Internal Medicine
Immunoglobulin heavy chain amyloidosis (AH amyloidosis) is an extremely rare subtype of immunoglobulin-derived amyloidosis and there is limited literature on how to diagnose and manage this disorder. We describe a rare case of AH amyloidosis with amyloid
Francisco Laranjeira   +6 more
doaj   +1 more source

Engineered Bacterial Ligand From Streptococcus pneumoniae on Macroporous Resins for Selective Affinity Capture of Secretory IgA

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Secretory immunoglobulin A (sIgA) is a promising emerging biopharmaceutical candidate, but it currently lacks a standardized platform for purification. To address this, a novel affinity chromatography resin was developed by immobilizing protein variants of the Streptococcus pneumoniae surface protein, SpsA, as an affinity ligand.
David Scheich   +8 more
wiley   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn   +5 more
wiley   +1 more source

Effect of Precursor Structure on Pore Evolution of Pitch‐Derived Porous Carbon Nanoarchitectonics

open access: yesCarbon and Hydrogen, EarlyView.
Precursor microstructure–regulated activation and pore evolution in pitch‐derived porous carbon, demonstrating the superior nanoarchitectonics at moderate mesophase content. ABSTRACT Developing high‐performance porous carbons (PCs) requires precise microstructural control, which can be effectively understood within the framework of nanoarchitectonics ...
Yajie Duan   +4 more
wiley   +1 more source

Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire. [PDF]

open access: yesNat Commun, 2023
Rodriguez OL   +12 more
europepmc   +1 more source

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