In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi +4 more
wiley +1 more source
Epstein-Barr virus<sup>+</sup> inflammatory follicular dendritic cell sarcoma with clonal immunoglobulin heavy chain gene rearrangement: A case report and literature review. [PDF]
Ye Q, Zhao J, He J, Zhang W.
europepmc +1 more source
A comparison of capillary electrophoresis and next-generation sequencing in the detection of immunoglobulin heavy chain H and light chain κ gene rearrangements in the diagnosis of classic hodgkin's lymphoma. [PDF]
Zhang JJ +7 more
europepmc +1 more source
The Immunoglobulin Heavy Chain Constant Region Affects Kinetic and Thermodynamic Parameters of Antibody Variable Region Interactions with Antigen [PDF]
Marcela Torres +3 more
openalex +1 more source
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Characterization of a factor VIII/immunoglobulin heavy chain μ double-knockout mouse model of hemophilia A for long-term exposure to factor VIII proteins. [PDF]
Monica L +10 more
europepmc +1 more source
LICHEN enables light-chain immunoglobulin sequence generation conditioned on the heavy chain and experimental needs [PDF]
Henriette Capel +11 more
openalex +1 more source
High-throughput sequencing of murine immunoglobulin heavy chain transcripts using single side unique molecular identifiers on an Ion Torrent PGM [PDF]
Jean-Philippe Bürckert +7 more
openalex +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source

