Results 261 to 269 of about 116,527 (269)
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Addition of glucosamine and mannose to nascent immunoglobulin heavy chains
Biochemistry, 1977We have investigated the process of protein glycosylation in an attempt to answer the question of whether glucosamine and mannose are added to nascent chains prior to chain completion or only to completed chains after release from the ribosome. The MPC 11 mouse plasmacytoma cell line used in these studies synthesizes a glycosylated gamma2b heavy chain ...
W. M. Kuehl, L. W. Bergman
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Immunoglobulin heavy-chain switching in pre-B leukaemias
Nature, 1983Immunoglobulin gene expression is initiated in pre-B cells by rearrangements of heavy-chain variable genes V, D and J, for transcription together with the constant region gene C mu (refs 1-7). The subsequent joining of light-chain V-J genes in the kappa or lambda families leads to formation of complete IgM molecules, which are then expressed on the ...
Max D. Cooper +3 more
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Balanced Synthesis of Light and Heavy Chains of Immunoglobulin G
Nature, 1967WE have already investigated the production of immunoglobulin G (IgG) by mouse plasma cell tumour 5563 and have shown that light chains are released autonomously from polyribosomes into a pool of free light chains. The time course of incorporation of radioactive amino-acids into free light chain and the myeloma protein indicated that the pool of free ...
Brigitte A. Askonas, A. R. Williamson
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The Transcription Factor, Bright, and Immunoglobulin Heavy Chain Expression
Immunologic Research, 2001Bright, or B cell regulator of immunoglobulin heavy chain transcription, is a B lymphocyte-specific protein first discovered for its ability to increase immunoglobulin transcription three- to sevenfold in antigen-activated B cells. It interacts with DNA through an ARID, or A/T-rich interaction domain, and is the only member of a previously undescribed ...
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New views of the immunoglobulin heavy-chain switch
Nature, 1982Max D. Cooper +3 more
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Association of variable and constant regions of immunoglobulin heavy chains
Immunochemistry, 1972An-Chuan Wang +3 more
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Technique for the detection of deleted immunoglobulin heavy chains
Biochemistry, 1973openaire +3 more sources
STRUCTURAL STUDIES OF IMMUNOGLOBULIN G, M AND A HEAVY CHAINS
Annals of the New York Academy of Sciences, 1971C. Wolfenstein +5 more
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