Results 71 to 80 of about 130,645 (352)

Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. [PDF]

open access: yes, 1993
We have generated transgenic mice that express the immunoglobulin (Ig)M heavy chain and kappa light chain genes coding for a human IgM rheumatoid factor (RF), Les.
Carson, DA   +6 more
core   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity

open access: yesHaematologica, 2019
Chronic lymphocytic leukemia cells have an altered energy metabolism compared to normal B cells. While there is a growing understanding of the molecular heterogeneity of the disease, the extent of metabolic heterogeneity and its relation to molecular ...
Junyan Lu   +5 more
doaj   +1 more source

Sequencing B cell receptors from ferrets (Mustela putorius furo).

open access: yesPLoS ONE, 2020
The domestic ferret (Mustela putorius furo) provides a critical animal model to study human respiratory diseases. However immunological insights are restricted due to a lack of ferret-specific reagents and limited genetic information about ferret B and T
Julius Wong   +5 more
doaj   +1 more source

Diversity and structure of human T-Cell receptor β-chain variable region genes [PDF]

open access: yes, 1986
The nucleotide sequences of 27 T-cell receptor β cDNA clones isolated from a human peripheral lymphocyte library were determined and compared to five additional published sequences. These cDNA clones represent 22 distinct T-cell receptor β-chain variable
Concannon, Patrick   +3 more
core  

Review of Immunoinformatic approaches to in-silico B-cell epitope prediction [PDF]

open access: yes, 2007
In this paper, the current state of in-silico, B-cell epitope prediction is discussed. Recommendations for improving some of the approaches encountered are outlined, along with the presentation of an entirely novel technique, which uses molecular ...
Rick Reitmaier
core   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

Expression cloning and production of human heavy-chain-only antibodies from murine transgenic plasma cells [PDF]

open access: yes, 2016
Several technologies have been developed to isolate human antibodies against different target antigens as a source of potential therapeutics, including hybridoma technology, phage and yeast display systems.
Dubravka Drabek   +7 more
core   +4 more sources

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

open access: yesAdvanced Materials Interfaces, EarlyView.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins   +8 more
wiley   +1 more source

Two Cases of Heavy Chain MGUS

open access: yesCase Reports in Oncological Medicine, 2016
Heavy chain diseases are rare variants of B-cell lymphomas that produce one of three classes of immunoglobulin heavy chains, without corresponding light chains. We describe two patients with asymptomatic heavy chain monoclonal gammopathy.
Jan Van Keer   +4 more
doaj   +1 more source

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