Results 311 to 320 of about 136,602 (331)

T-cell idiotypes are linked to immunoglobulin heavy chain genes

Nature, 1976
FOUR gene clusters have products that seem to participate in antigen binding on T or B lymphocytes. Three (the genes coding for the heavy and light chains of immunoglobulin molecules) are known to code for structural elements of B-cell receptors for antigen.
Hans Binz, Hans Wigzell, Hervé Bazin
openaire   +3 more sources

Mechanisms for feedback inhibition of the immunoglobulin heavy chain locus

Current Opinion in Immunology, 2004
The production of immunoglobulin heavy chain (IgH) protein in pro-B cells provides feedback to terminate further V(H) gene recombination. This phenomenon is referred to as allelic exclusion. The chromatin structure of the V(H) genes regulates their recombination potential, hence alterations in chromatin are a key factor in allelic exclusion.
Dipanjan Chowdhury, Ranjan Sen
openaire   +3 more sources

Immunoglobulin heavy-chain switching in pre-B leukaemias

Nature, 1983
Immunoglobulin gene expression is initiated in pre-B cells by rearrangements of heavy-chain variable genes V, D and J, for transcription together with the constant region gene C mu (refs 1-7). The subsequent joining of light-chain V-J genes in the kappa or lambda families leads to formation of complete IgM molecules, which are then expressed on the ...
Max D. Cooper, Mitsufumi Mayumi, Hiromi Kubagawa, William M. Crist   +3 more
openaire   +3 more sources

Temporal relationship of translation and glycosylation of immunoglobulin heavy and light chains.

, 1978
: The initial glycosylation of MPC 11 gamma 2b heavy chains occurs quantitatively in vivo when the nascent heavy chains reach a size of approximately 38 000 daltons.
Bergman Lw, Kuehl Wm
semanticscholar   +1 more source

Genetic control of variable and constant regions of immunoglobulin heavy chains.

Nature: New biology, 1971
R. Mage, G. Young-Cooper, C. Alexander
semanticscholar   +1 more source

The Transcription Factor, Bright, and Immunoglobulin Heavy Chain Expression

Immunologic Research, 2001
Bright, or B cell regulator of immunoglobulin heavy chain transcription, is a B lymphocyte-specific protein first discovered for its ability to increase immunoglobulin transcription three- to sevenfold in antigen-activated B cells. It interacts with DNA through an ARID, or A/T-rich interaction domain, and is the only member of a previously undescribed ...
openaire   +3 more sources

Identification and genetic control of allotypic specificites on two variable region subgroups of rabbit immunoglobulin heavy chains

European Journal of Immunology, 1972
Byung S. Kim, S. Dray
semanticscholar   +1 more source

Cancer cell expressions of immunoglobulin heavy chains with unique carbohydrate-associated biomarker

Cancer Biomarkers, 2009
Gregory M. Lee, Bixia Ge
semanticscholar   +1 more source

Genes for immunoglobulin heavy chains and for α1-antitrypsin are localized to specific regions of chromosome 14q

Nature, 1982
D. Cox, V. Markovic, I. Teshima
semanticscholar   +1 more source

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

Nature, 1984
M. Reth, F. Alt
semanticscholar   +1 more source