Results 311 to 320 of about 172,498 (401)

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

Monoclonal immunoglobulins on red blood cells: a potential supplementary diagnostic indicator for monoclonal gammopathies. [PDF]

Front Immunol
Bing B, Yang X, Wang C, Xu L, Cheng S, Liu Y, Wang Q, Zhai C, Zhao B, Wang R, Sun J.   +10 more
europepmc   +1 more source

Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death

The FEBS Journal, EarlyView.
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa, Haruka Nakagawa, Chin Mun Yee, Keiko Kuwata, Kiyotaka Hitomi   +4 more
wiley   +1 more source

Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data. [PDF]

Commun Biol
Dudzic P, Chomicz D, Bielska W, Jaszczyszyn I, Zieliński M, Janusz B, Wróbel S, Le Pannérer MM, Philips A, Ponraj P, Kumar S, Krawczyk K.   +11 more
europepmc   +1 more source

Immune‐related toxicity profile after haematopoietic stem cell transplantation in patients with B‐ALL given combination immunotherapy with rituximab, inotuzumab and blinatumomab

British Journal of Haematology, EarlyView.
Olayinka Okeleji, David McCall, Branko Cuglievan, Amber Gibson, Demetrios Petropoulos, Priti Tewari, Jeremy Connors, Irtiza N. Sheikh   +7 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

Serum and Tissue Light-Chains as Disease Biomarkers in AL Amyloidosis. [PDF]

Int J Mol Sci
Aimo A, Ferrari Chen YF, Chianca M, Mori F, Pucci A, Castiglione V, Musetti V, Caponi L, Fabiani I, Vergaro G, Franzini M, Emdin M, Cardinale D.   +12 more
europepmc   +1 more source

Next‐generation sequencing‐based IG clonality analysis to discriminate reactive infiltrates from minimal lymphoma involvement in paired lymphoma and bone marrow biopsies; a EuroClonality‐NGS Working Group study

Histopathology, EarlyView.
Next‐generation sequencing (NGS) immunoglobulin clonality analysis can help resolve ambiguous bone marrow staging biopsies for B‐cell lymphoma. In this study, paired analysis of the primary lymphoma and bone marrow helped to detect lymphoma involvement in cases with inconclusive morphology and immunohistochemistry, making it a valuable tool for ...
Michiel van den Brand, Meilinde Leenders, Jos Rijntjes, Jeroen A.C.W. Luijks, Anton W. Langerak, Konnie M. Hebeda, Patricia J.T.A. Groenen   +6 more
wiley   +1 more source

The evolutionary history of IGKC in mammals reveals ancient duplications and remarkable divergence in lagomorphs. [PDF]

Front Immunol
Pinheiro A, Borges JR, Marques JP, Esteves PJ.   +3 more
europepmc   +1 more source