Results 321 to 330 of about 280,511 (396)

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Decoding B Cells in Autoimmune Diseases Through ScRNA + BCR-Seq: Current Knowledge and Future Directions. [PDF]

Cells
Quan K, Wang H, Su P, Xu Y, Yao X.
europepmc   +1 more source

A Single‐Center Retrospective Study of the Investigation of Monoclonal B‐Cell Lymphocytosis (MBL) and Chronic Lymphocytic Leukemia (CLL) in Southwestern Ontario: Are We Over‐Investigating?

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Monoclonal B‐cell lymphocytosis (MBL) is a common cause of lymphocytosis in older individuals. Although cytogenetic/molecular testing is usually reserved for patients requiring treatment, recent studies suggest that early testing may have a prognostic benefit in MBL and early‐stage chronic lymphocytic leukemia (CLL).
Ortenc Hoxha, Mrinal Lad, Benjamin D. Hedley, Ian H. Chin‐Yee, Cyrus C. Hsia, Benjamin Chin‐Yee   +5 more
wiley   +1 more source

Nanobody-based heavy chain antibodies and chimeric antibodies. [PDF]

Immunol Rev
Koch-Nolte F.
europepmc   +1 more source

Evaluation of MYD88 p.L265P detection by digital droplet polymerase chain reaction in cerebrospinal fluid for integrated diagnosis of primary large B‐cell lymphoma of the central nervous system

British Journal of Haematology, EarlyView.
Vincent Harlay, Catherine Gallardo, Nathalie Beaufils, Alexandre Astier, Benoit Testud, Amira Amri, Shirley Fritz, Norman Abbou, Philippe Robert, Jeremy Garcia, Patrice Roll, L'houcine Ouafik, Laurence Schenone, Gregorio Petrirena, Alexandre Bertucci, Céline Bequet, Olivier Chinot, Emeline Tabouret, Isabelle Nanni, Romain Appay, Elise Kaspi, Diane Frankel   +21 more
wiley   +1 more source

Outcomes of allogeneic haemopoietic transplant for chronic lymphocytic leukaemia in the modern era

Internal Medicine Journal, EarlyView.
Abstract Background Allogeneic haemopoietic stem cell transplantation (HSCT) is an effective therapy with curative potential for patients with high‐risk or relapsed/refractory chronic lymphocytic leukaemia (CLL). There are limited data on the use and outcomes of HSCT in the modern era of CLL treatment.
Luani Barge, Steven Tran, Glen Kennedy, David Ritchie, David Gottlieb, Sam Milliken, Andrew Spencer, Duncan Purtill, Travis Perera, Richard Doocey, Stephen Larsen, Andrew Butler, Peter Bardy, Matthew Greenwood, Simon Durrant, Cameron Curley, Caroline Stewart, Constantine Tam, Shalini Balendran, Pietro R. Di Ciaccio, Sushrut Patil, Min‐Hi Han, Nada Hamad   +22 more
wiley   +1 more source

ImmunoMatch learns and predicts cognate pairing of heavy and light immunoglobulin chains

Guo D, Dunn-Walters DK, Fraternali F, Ng JCF.   +3 more
europepmc   +1 more source

Idiopathic Nodular Glomerulosclerosis in a Long-term Passive Smoker With Recently Diagnosed Hypertension: A Case Report. [PDF]

J Investig Med High Impact Case Rep
Vakhshoori M, Hanna PE, Obaidi Z, Chen Wongworawat Y, Abdipour A, Norouzi S.   +5 more
europepmc   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

Immunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho, Valéria Oliveira Silva, Luis Fernando de Macedo Brigido, Elizabeth De Gaspari   +3 more
wiley   +1 more source

METTL3/YTHDF3 m6A axis promotes ferroptosis in diabetic kidney disease by stabilizing TfR1

Journal of Diabetes Investigation, EarlyView.
METTL3/YTHDF3 m6A axis promoted ferroptosis in DKD by stabilizing TfR1, which could provide a reference for DKD treatment. ABSTRACT Objective Diabetic kidney disease (DKD) is a common complication of diabetes. N6‐Methyladenosine (m6A) modification is a widely studied epigenetic mechanism.
Jinmei Zhang, Xiaoping Zhou, Bin Wang, Yan Yin, Daihao Wei, Kun Li   +5 more
wiley   +1 more source