Progress in spondylarthritis immunopathogenesis of spondyloarthritis: which cells drive disease? [PDF]
, 2009 Spondyloarthritides, or SpA, form a cluster of chronic inflammatory diseases with the axial skeleton as the most typical disease localisation, although extra-articular manifestations such as intestinal inflammation may frequently occur during the course ...
Melis, Lode, Elewaut, Dirk
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Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites. [PDF]
, 1985 Three monoclonal antibodies that react with previously undefined antigenic determinants on the clathrin molecule have been produced and characterized. They were isolated from a fusion between myeloma cells and popliteal lymphocytes from SJL mice that had
Brodsky, Frances
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Characterization of Tear Immunoglobulins in a Small-Cohort of Keratoconus Patients
Scientific Reports, 2020 Keratoconus (KC) is classically considered a non-inflammatory condition caused by central corneal thinning that leads to astigmatism and reduced visual acuity.
Tina B. McKay +4 more
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Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattle. [PDF]
PLoS ONE, 2013 Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases.
Akiko Sano +7 more
doaj +1 more source
Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation. [PDF]
PLoS ONE, 2012 Beside the production of complete immunoglobulins IgG, IgE, IgA, IgM and IgD, consisting of tetrameric heterodimers of immunoglobulin heavy and light chains, B cells also secrete immunoglobulin free light chains (Ig-fLC).
Marco Thio +5 more
doaj +1 more source
Long-term cultures of murine fetal liver retain very early B lymphoid phenotype. [PDF]
, 1984 Long-term cultures of murine fetal liver have been successfully established using a modification of our in vitro bone marrow culture system (14, 15).
Denis, KA +3 more
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, 2018 Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) may be directly pathogenic.
Amara, Khaled +17 more
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Frontiers in ImmunologyPoultry immunoglobulin genes undergo diversification through homologous recombination (HR) and somatic hypermutation (SHM). Most animals share a similar system in immunoglobulin diversification, with the rare exception that human and murine ...
Hidetaka Seo +2 more
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Immune Repertoire Profiling Reveals that Clonally Expanded B and T Cells Infiltrating Diseased Human Kidneys Can Also Be Tracked in Blood. [PDF]
PLoS ONE, 2015 Recent advances in high-throughput sequencing allow for the competitive analysis of the human B and T cell immune repertoire. In this study we compared Immunoglobulin and T cell receptor repertoires of lymphocytes found in kidney and blood samples of 10 ...
Johannes Weinberger +10 more
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Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line [PDF]
, 1984 We demonstrated that a subclone of an Abelson murine leukemia virus-transformed B-lymphoid cell line switched from mu to gamma 2b expression in vitro, by the classical recombination-deletion mechanism.
Alt, Frederick W. +5 more
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