Results 61 to 70 of about 280,511 (396)

Presence of two different immunoglobulin heavy chains in individual cells of established human hematopoietic cell lines.

Journal of Immunology, 1968
Presence of γ-, α- and µ-heavy chains of immunoglobulin was examined in cultured cells of established human hematopoietic cell lines. Combinations of a fluorescein-conjugated antibody of one specificity and a tetramethylrhodamine-conjugated antibody of
M. Takahashi, N. Tanigaki, Yasuo Yagi, George E. Moore, David Pressman   +4 more
semanticscholar   +1 more source

Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4 [PDF]

, 2004
86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally
Allen RC, Aruffo A, Bonhomme D, Fuleihan R, Lin Q, Mayer L, Ramesh N, Seyama K, Webster ADB, WHO Scientific Group.   +9 more
core   +3 more sources

Identification of two rate-limiting steps in the degradation of partially folded immunoglobulin light chains

Frontiers in Cell and Developmental Biology, 2022
Antibody monomers are produced from two immunoglobulin heavy chains and two light chains that are folded and assembled in the endoplasmic reticulum This process is assisted and monitored by components of the endoplasmic reticulum quality control ...
Melissa J. Mann, Ashley R. Flory, Christina Oikonomou, Christina Oikonomou, Candace A. Hayes, Chris Melendez-Suchi, Linda M. Hendershot, Linda M. Hendershot   +7 more
doaj   +1 more source

Non-Gaussian polymers described by alpha-stable chain statistics: model, applications and effective interactions in binary mixtures [PDF]

Phys. Rev. E, 91, 5, 052602 (2015), 2015
The Gaussian chain model is the classical description of a polymeric chain, which provides the analytical results regarding end-to-end distance, the distribution of segments around the mass center of a chain, coarse grained interactions between two chains and effective interactions in binary mixtures.
arxiv   +1 more source

Significant differences in physicochemical properties of human immunoglobulin kappa and lambda CDR3 regions

Frontiers in Immunology, 2016
Antibody variable regions are composed of a heavy and a light chain and in humans there are two light chain isotypes: kappa and lambda. Despite their importance in receptor editing, the light chain is often overlooked in the antibody literature, with the
Catherine L Townsend, Julie MJ Laffy, Yu-Chang Bryan Wu, Joselli Silva O'Hare, Victoria Martin, David Kipling, Franca Fraternali, Deborah K Dunn-Walters   +7 more
doaj   +1 more source

Isolation, Production, and Characterization of Serum Immunoglobulin M (IgM) of Indian Major Carp Cirrhinus mrigal (MRIGAL)

Advances in Pharmacological and Pharmaceutical Sciences, 2022
A method for the isolation of immunoglobulin M (IgM) in Indian major carp Cirrhinus mrigal (mrigal) serum to produce polyclonal antibodies is described in the present study.
Prasanna Shama Khandige, K. M. Shankar, P. Suresh Babu, Vandana Sadananda, S. Gowrish   +4 more
doaj   +1 more source

Structural insights and biomedical potential of IgNAR scaffolds from sharks [PDF]

, 2014
Peer reviewedPublisher ...
Barelle, Caroline, Empting, Martin, Grzeschik, Julius, Kolmar, Harald, Könning, Doreen, Zielonka, Stefan   +5 more
core   +1 more source

Detection of intracellular IgD using flow cytometry could be a novel and supplementary method to diagnose IgD multiple myeloma

BMC Cancer, 2018
Background We examined whether detecting the heavy chain of cytoplasmic immunoglobulin D (IgD) by flow cytometry could be used as a supplemental method to diagnose IgD multiple myeloma (MM).
Wei Wang, Chun-Xia Zhang, Zhen-Ling Li, Ming Gong, Yi-Gai Ma   +4 more
doaj   +1 more source

Sequence relationships among the variable regions of immunoglobulin heavy chains from various mammalian species.

Proceedings of the National Academy of Sciences of the United States of America, 1972
Immunoglobulin heavy chains of myeloma proteins from dogs and cata have been subjected to automated sequence analysis. When the results were compared with human heavy-chain sequences, all the dog and cat proteins could be unequivocally assigned to the V ...
J. Kehoe, J. Capra
semanticscholar   +1 more source

The antibody loci of the domestic goat (Capra hircus) [PDF]

, 2018
The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M., Hammond, John A., Philp, Rebecca L., Schwartz, John C., Smith, Timothy P.L.   +4 more
core   +1 more source