Attractors in residual interactions explain the differentially-conserved stability of Immunoglobulins [PDF]
Proteins belonging to immunoglobulin superfamily(IgSF) show remarkably conserved nature both in their folded structure and in their folding process, but they neither originate from very similar sequences nor demonstrate functional conservation. Treating proteins as fractal objects, without studying spatial conservation in positioning of particular ...
arxiv
Bos taurus genome sequence reveals the assortment of immunoglobulin and surrogate light chain genes in domestic cattle [PDF]
Background The assortment of cattle immunoglobulin and surrogate light chain genes has been extracted from the version 3.1 of Bos taurus genome sequence as a part of an international effort to sequence and annotate the bovine genome.
Ekman, Anna+3 more
core +3 more sources
Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi+7 more
wiley +1 more source
Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension
Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen+2 more
wiley +1 more source
Integrable su(2)-invariant spin chains and the Haldane conjecture [PDF]
We perform a systematic exact algebraic search for integrable spin-S chains which are isotropic in spin space, i.e. are su(2)-invariant. The families of spin chains found for S < 14 support recent arguments in favour of the complete classification of all such integrable chains.
arxiv
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy. [PDF]
Recently the minor B cell subpopulation that expresses the CD5 (Leu-1) antigen has been implicated as a source of IgM autoantibodies. Chronic lymphocytic leukemia (CLL), the most common leukemia in humans, represents a malignancy of small B lymphocytes ...
Carson, DA+3 more
core
Super‐Resolution Goes Viral: T4 Virus Particles as Versatile 3D‐Bio‐NanoRulers
Various super‐resolution fluorescence microscopy methods achieve nanoscale resolution, vital for visualizing subcellular structures. Choosing suitable biological standards is challenging, demanding precise geometry and specific labeling capabilities. Utilizing T4 bacteriophage as a 3D‐Bio‐NanoRuler is proposed.
José Ignacio Gallea+10 more
wiley +1 more source
This review examines the fluid dynamic behavior within carbonaceous porous structures, linking structural characteristics to electrolyte transport and electrochemical performance. Specifically, it quantitatively assesses the effect of polyphenol derivatives‐harnessed multiscale pore structures on active surface utilization and electrochemical activity ...
Minjun Kim+3 more
wiley +1 more source
Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis [PDF]
<b>Background</b>: Serum electrophoretic profiles in cats are poorly characterized with respect to the protein components of the globulin fractions, and interpretation of the electrophoretograms has routinely been done in ignorance of the ...
Baker+36 more
core +1 more source
Shortwave Infrared Light Detection and Ranging Using Silver Telluride Quantum Dots
Post‐synthesis surface engineering and doping control significantly improve the performance of Ag₂Te CQD photodiodes, achieving a low dark current of 450 nA cm−2 at −0.5 V, an LDR exceeding 150 dB, and a rapid response speed of ≈25 ns. A proof‐of‐concept LiDAR demonstration in the SWIR using a nanosecond diode laser, achieves decimetre‐level resolution
Yongjie Wang+6 more
wiley +1 more source