Results 151 to 160 of about 118,116 (256)

Data from CAR T cells Targeting Human Immunoglobulin Light Chains Eradicate Mature B-cell Malignancies While Sparing a Subset of Normal B Cells

, 2023
Raghuveer Ranganathan, Peishun Shou, Sarah Ahn, Chuang Sun, John B. West, Barbara Savoldo, Gianpietro Dotti   +6 more
openalex   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Periorbital Purpura as a Key Diagnostic Clue in Immunoglobulin Light Chain Amyloidosis. [PDF]

JMA J
Miyaue K, Isono H.
europepmc   +1 more source

A risk stratification for systemic immunoglobulin light‐chain amyloidosis with renal involvement [PDF]

, 2019
Ting Li, Xianghua Huang, Qingwen Wang, Liang Zhao, Guisheng Ren, Wencui Chen, Pengfei Zheng, Minlin Zhou, Qi Jiang, Ru Yin, Zhihong Liu   +10 more
openalex   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Budd-Chiari Syndrome as the Presenting Feature of Systemic Immunoglobulin Light Chain Amyloidosis. [PDF]

Eur J Case Rep Intern Med
Miranda JL, Salvado C, Carmo F, Guedes A, Moreira A, Guimarães Costa T, Silva L.   +6 more
europepmc   +1 more source

Salts enhance both protein stability and amyloid formation of an immunoglobulin light chain

, 2008
Laura A. Sikkink, Marina Ramı́rez-Alvarado   +1 more
openalex   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Characterization of extensive diversity in immunoglobulin light chain variable germline genes across biomedically important mouse strains. [PDF]

Immunohorizons
Kos JT, Safonova Y, Shields K, Silver CA, Lees WD, Collins AM, Watson CT.   +6 more
europepmc   +1 more source

Immunoglobulin light chain amyloidosis: 2018 Update on diagnosis, prognosis, and treatment [PDF]

, 2018
Morie A. Gertz
openalex   +1 more source