Results 151 to 160 of about 209,782 (306)

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Long-term risk of myelodysplasia in melphalan-treated patients with immunoglobulin light-chain amyloidosis

, 2008
M. A. Gertz, M. Q. Lacy, J A Lust, P R Greipp, T. E. Witzig, R. A. Kyle   +5 more
openalex   +2 more sources

First report of safety and efficacy of daratumumab in 2 cases of advanced immunoglobulin light chain amyloidosis [PDF]

, 2016
Taimur Sher, Brooke Fenton, Adnan Akhtar, Morie A. Gertz   +3 more
openalex   +1 more source

A Case of Solitary Plasmacytoma of Bone Showing Coexpression of Both Immunoglobulin Light Chains [PDF]

, 2021
Ryota Matsuoka, Noriaki Sakamoto, Takayasu Kato, Shigeru Chiba, Masayuki Noguchi   +4 more
openalex   +1 more source

Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR‐NFκB Pathway

Advanced Science, EarlyView.
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen, Nian Liu, Qian Tao, Jie Wu, Jinyu Huang, Can Lu, Qiuqiu Li, Liangfang Shen, Xiang Chen, Cong Peng   +9 more
wiley   +1 more source

Immunoglobulin Light Chain Amyloidosis: Diagnosis and Risk Assessment. [PDF]

J Natl Compr Canc Netw, 2023
Zanwar S, Gertz MA, Muchtar E.
europepmc   +1 more source

Germline polymorphism in the immunoglobulin kappa and lambda loci explain variation in the expressed light chain antibody repertoire [PDF]

Eric Engelbrecht, Oscar L. Rodriguez, William Lees, Zach Vanwinkle, Kaitlyn Shields, Steven Schultze, William S. Gibson, David R. Smith, Uddalok Jana, Swati Saha, Ayelet Peres, Gur Yaari, Melissa L Smith, Corey T. Watson, Eric Engelbrecht, Oscar L. Rodriguez, William Lees, Zach Vanwinkle, Kaitlyn Shields, Steven Schultze, William S. Gibson, David R. Smith, Uddalok Jana, Swati Saha, Ayelet Peres, Gur Yaari, Melissa L Smith, Corey T. Watson   +27 more
openalex   +1 more source

The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair

Advanced Science, EarlyView.
Synthesis of an innovative three‐layer composite antiadhesion barrier (plasmid DNA@E–H–E′) is schematically illustrated, highlighting its reactive‐oxygen‐species‐responsive, unidirectional interleukin‐37 delivery to enhance fibroblast autophagy, thereby effectively preventing tendon adhesion and promoting scarless tendon repair.
Zhenyu Sun, Jingwen Liu, Liang Chen, Zhen Wang, Fei Wang, Shen Liu   +5 more
wiley   +1 more source

Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005. [PDF]

Nat Commun, 2023
Pradhan T, Sarkar R, Meighen-Berger KM, Feige MJ, Zacharias M, Reif B.   +5 more
europepmc   +1 more source

Amino-terminal identity of co-existent amyloid and non-amyloid immunoglobulin κ light chain deposits. A human disease to study alterations of protein conformation

, 1997
Kaplan, B., Vidal, R., Kumar, A., GHISO, J, FRANGIONE, B, Gallo, G.   +5 more
openalex   +2 more sources