Results 101 to 110 of about 423,364 (313)

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis

, 2009
Objectives: To assess the possible association of killer immunoglobulin-like receptor (KIR) genes, specifically KIR3DL1, KIR3DS1 and KIR3DL2, with ankylosing spondylitis (AS).
Pointon, JJ, Farrar, C, Sun, JY, Harvey, D, Brown, M A, Sleator, C, Sleator, C., Middleton, D, Brown, MA, Meenagh, A, Wordsworth, BP, Meenagh, A., Senitzer, D., Pointon, J. J., Senitzer, D, Wordsworth, B. P., Farrar, C., Sun, J. Y., Middleton, D., Wordsworth, Bryan, Harvey, D.   +20 more
core   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

Accuracy of immunoglobulin M and immunoglobulin A of saliva in early diagnosis of dengue: Systematic Review and Meta-analysis

Anais da Academia Brasileira de Ciências, 2018
The objective of the study was to conduct a systematic review to synthesize the current evidence on the accuracy of IgM and IgA to early diagnosis the dengue virus. The review protocol was registered at PROSPERO (CRD 42015024808). We searched for studies
TAMY COLONETTI, BELISE V.E. ROCHA, ANTÔNIO J. GRANDE, MARIA C.M. ALEXANDRE, EDUARDO R. DONDOSSOLA, KRISTIAN MADEIRA, MARIA I. ROSA   +6 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Conditioning murine B cells for immunoglobulin A production In vitro

, 2012
The respiratory mucosa is continuously exposed to a myriad of pathogens and allergens that are inhaled during respiration. B cells of the immune system produce immunoglobulin A (IgA) that protects the respiratory mucosa from inhaled pathogens and ...
Goh, Wil
core   +1 more source

Structural investigation of the molecular mechanisms underlying titin elasticity and signaling [PDF]

, 2010
Titin is a giant protein that spans >1µm from the Z-disc to the M-line, forming an intrasarcomeric filament system in vertebrate striated muscle, which is not only essential for the assembly of the sarcomere, but also critical for myofibril signaling and
Castelmur, Eleonore von
core   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Acute reduction in secretory immunoglobulin A following smoking cessation

, 2004
Smokers report an increase in upper respiratory infections in the early phase of stopping smoking. One possible cause is a depletion in secretory immunoglobulin A (S-IgA) which has been observed in one study.
Steptoe, A, Ussher, M, Hucklebridge, F, Clow, A, McEwen, B, West, R, Evans, P   +6 more
core  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Effect of clozapine on immunoglobulin M plasma levels [PDF]

, 2016
Clozapine is an atypical antipsychotic medication indicated for the treatment of patients who fail to respond to standard antipsychotic treatment. It possesses immunomodulatory properties and requires regular counts of white blood cells and absolute ...
Lozano, R., Pascual, A., Santacruz, M.J., Marin, R.   +3 more
core   +1 more source