Results 91 to 100 of about 24,521,037 (258)

Detection of rubella virus-specific immunoglobulin M antibodies with a baculovirus-expressed E1 protein

, 1996
The structural proteins of rubella virus (RV) were expressed in insect cells by using the baculovirus expression vector system. The recombinant E1 envelope glycoprotein was purified by immunoaffinity chromatography and used to detect RV-specific ...
Salmi, Aimo, Oker-Blom, Christian, Schmidt, Michel, Lindqvist, Christer   +3 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions [PDF]

, 2021
Key messages: PANS (Pediatric Acute onset Neuropsychiatric Syndrome)/PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections) is described as an abrupt, dramatic onset of obsessive-compulsive disorder (OCD) or ...
Grøvan, Anette Olsson, Frønsdal, Katrine Bjørnebek   +1 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Relationship between renal deposition of complement C3， IgG， IgM and pathology in IgA nephropathy

Linchuang shenzangbing zazhi, 2022
ObjectiveTo explore the effects of complement C3， IgG and IgM renal deposition on renal pathological injury in patients with IgA nephropathy.MethodsFrom August 1， 2019 to January 30， 2021， retrospective review was performed for electronic medical records
Fang-cao Lu, Hong-ling Yuan
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Immunoglobulin levels as related to age in nonhuman primates in captivity. I. Chimpanzees

, 1974
Immunoglobulin levels in the sera of 60 chimpanzees between 1 and 12 yr of age were determined by single radial immunodiffusion, using antisera against class specific determinants of human immunoglobulins showing a reaction of identity between the human ...
Berg, P. van den, Radl, J., Voormolen Kalova, M.   +2 more
core  

6th International Immunoglobulin Symposium: poster presentations [PDF]

, 2009
The posters presented at the 6th International Immunoglobulin Symposium covered a wide range of fields and included both basic science and clinical research.
van Schaik, I N, Yuki, Nobuhiro, Winkelmann, A, N. Yuki, A. Durandy, Käsermann, F., Durandy, Anne, Quinti, I., Fernandez-Cruz, E, Durandy, A., Danieli, Maria Giovanna, A. Winkelmann, Cantoni, N, M. G. Danieli, Kaesermann, F., Käsermann, F, Helbert, M., Späth, P, Späth, Paul, J. Bayry, P. Spath, van Schaik, I.N., Fernández-Cruz, Eduardo, QUINTI, Isabella, Quinti, I, Kaveri, S. V., Durandy, A, Bussel, J B, Bayry, J, I. N. Van Schaik, Cantoni, N., J. B. Bussel, Helbert, M, Peter Hh, Bussel, J.B., Winkelmann, A., Spaeth, P., R. Sorensen, Yuki, N, Peter, Hans-Hartmut, Sorensen, R., Schaik, Ivo N. van, M. Helbert, Bayry, J., Yuki, N., Sorensen, R, Kaveri, S V, S. V. Kaveri, Salama, A., E. Fernandez Cruz, Salama, A, A. Salama, Kaveri, S.V., Fernandez-Cruz, E., Peter, H.H., Winkelmann, Aline, Danieli, M.G., Danieli, M G, F. Kasermann, Helbert, Matthew, Peter, H-H, N. Cantoni, Bussel, J. B., Salama, Abdulgabar, Späth, Peter Julius   +64 more
core   +1 more source