Results 71 to 80 of about 24,521,037 (258)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Functionality of Immunoglobulin G and Immunoglobulin M Antibody Physisorbed on Cellulosic Films

Frontiers in Bioengineering and Biotechnology, 2017
The functionality and aging mechanism of antibodies physisorbed onto cellulosic films was investigated. Blood grouping antibodies immunoglobulin G (IgG) and immunoglobulin M (IgM) were adsorbed onto smooth cellulose acetate (CAF) and regenerated ...
Ziwei Huang, Vikram Singh Raghuwanshi, Gil Garnier   +2 more
doaj   +1 more source

Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports

Journal of Medical Case Reports, 2020
Background Immunoglobulin M multiple myeloma and Waldenström macroglobulinemia are two different hematological diseases with the common finding of an immunoglobulin M monoclonal gammopathy of unknown significance. However, clinical characteristics of the
Simona Elba, Alessia Castellino, Roberto Soriasio, Claudia Castellino, Margherita Bonferroni, Daniele Mattei, Giuliana Strola, Daniela Drandi, Nicola Mordini, Miriam Foglietta, Davide Rapezzi, Ivana Celeghini, Mariella Grasso, Fabrizio Giordano, Giulio Fraternali Orcioni, Massimo Massaia   +15 more
doaj   +1 more source

Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum [PDF]

, 2001
Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 ...
David R. Cavanagh, Cavanagh, D R, Ibrahim M. Elhassan, Elhassan, I M, Jana S. McBride, Kevin Marsh, Elhassan, A, Hviid, L, Khalil, E A T G, Ahmed Elhassan, Thor G. Theander, Cavanagh, David, Marsh, K, David E. Arnot, E. At Tahir G. Khalil, McBride, J S, Arnot, D E, Theander, T G, Lars Hviid, Dobano, C, Carlota Dobaño, Khalil, E A   +21 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Serum Immunoglobulin Levels in Iraqi Twins

, 2020
A study of serum immunoglobulin G, A, M and E levels in 107 pairs of Iraqi twins was carried out. The results suggest strong evidence for genetic as well as environ­mental factors in all four immunoglobulin ...
Al-Agidi, Saad K
core   +1 more source

Immunoglobulin levels as related to age in nonhuman primates in captivity. II. Rhesus monkeys

, 1974
Chemicals/CAS: immunoglobulin G, 97794-27-9; immunoglobulin M, 9007-85-6; Immunoglobulin A; Immunoglobulin D; Immunoglobulin G; Immunoglobulin M ...
Berg, P. van den, Radl, J., Voormolen Kalova, M.   +2 more
core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Influência do tipo de parto sobre a concentração de imunoglobulinas A, G e M no colostro materno Influence of type of delivery on A, G and M immunoglobulin concentration in maternal colostrum

Jornal de Pediatria, 2004
OBJETIVO: Verificar a influência do tipo de parto sobre a concentração das imunoglobulinas (Ig) A, G e M no colostro materno. MÉTODOS: Foram selecionadas 82 puérperas com idade cronológica entre 21 e 41 anos, idade gestacional de 37 ou mais semanas ...
Gabriel A. J. Striker, Lucy D. Casanova, Aparecida Tiemi Nagao   +2 more
doaj   +1 more source