Results 131 to 140 of about 27,788,716 (399)
BackgroundLassa fever (LF) is a devastating hemorrhagic viral disease that is endemic to West Africa and responsible for thousands of human deaths each year.
Luis M. Branco+8 more
semanticscholar +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
An Investigation into Outlier Elimination and Calculation Methods in the Determination of Reference Intervals using Serum Immunoglobulin A as a Model Data Collection [PDF]
Background: Reference intervals are essential to interpret diagnostic tests, but their determination has become controversial. Methods: In this paper parametric, non-parametric and robust reference intervals with Tukey and block elimination are calculated from a dataset of over 32,000 serum immunoglobulin A (IgA) measurements.
arxiv
RESPONS IMUNOGLOBULIN G (IgG) DAN IMUNOGLOBULIN M (IgM) AKIBAT LATIHAN SENAM PERNAFASAN [PDF]
This research aims at investigating the responses of immunoglobulin G and immunoglobulin M as the effects of breathing exercise. This is an experimental study using the pretest – posttest group design.
Prof. Dr., Jumhan Pida, M.Pd+1 more
core
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice [PDF]
We have examined the regulatory role of the individual components of the immunoglobulin antigen receptor in B-cell development by transgenic complementation of Rag-1 deficient (Rag-1⁻) mice. Complementation with a membrane µ heavy chain (µHC) gene allows
Baltimore, David+9 more
core
Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is
Ahima+45 more
core +1 more source
We have studied the role of secreted immunoglobulin (Ig)M in protection from infection with influenza virus and delineated the relative contributions of B-1 versus B-2 cell-derived IgM in this process.
N. Baumgarth+5 more
semanticscholar +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Six immunoassays for detecting immunoglobulin M antibodies to hepatitis E virus were evaluated. Serum samples representing acute infection by each of the 4 viral genotypes as well as nonacute hepatitis E virus infection constituted the test panels ...
J. Drobeniuc+7 more
semanticscholar +1 more source