Results 231 to 240 of about 214,734 (307)

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

A multivalent nanobody-drug conjugate to prevent and treat influenza virus infections. [PDF]

open access: yesProc Natl Acad Sci U S A
Harmand TJ   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Thyroid-stimulating immunoglobulins as a reliable predictive blood test for thyroid eye disease. [PDF]

open access: yesIndian J Ophthalmol
Madgar S   +9 more
europepmc   +1 more source

A Comprehensive Review of Monoclonal Gammopathy of Undetermined Significance. [PDF]

open access: yesJ Adv Pract Oncol
Noonan K   +5 more
europepmc   +1 more source

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