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Vaccine Design and Immunoinformatics
2021The emanation use of vaccines has shown tremendous applications of computational algorithms that can be used for amelioration of health globally. Vaccine Research has become a center area of research that embarks its applications to save several lives, reduced cost of treatment, and potential inhibitor of infectious diseases.
Fariya Khan, Ajay Kumar
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Immunoinformatic Identification of Potential Epitopes
2020Immunoinformatic plays a pivotal role in vaccine design and development. While traditional methods are exclusively depended on immunological experiments, they are less effective, relatively expensive, and time-consuming. However, recent advances in the field of immunoinformatics have provided innovative tools for the rational design of vaccine ...
Priti, Desai +3 more
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FROM IMMUNOINFORMATICS TO IMMUNOMICS
Journal of Bioinformatics and Computational Biology, 2003The immune system comprises a complex network of organs, specialized tissues, cells, and molecules. Its main function is to protect the organism from external and internal challenges and provides the interface between the organism and its environment. Foreign agents such as viruses, bacteria, fungi, or parasites may cause infection and disease. Foreign
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Immunoinformatics: A Brief Review
2014A large volume of data relevant to immunology research has accumulated due to sequencing of genomes of the human and other model organisms. At the same time, huge amounts of clinical and epidemiologic data are being deposited in various scientific literature and clinical records.
Namrata, Tomar, Rajat K, De
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Immunoinformatics Vaccine Design for Zika Virus
2023Zika virus (ZIKV) is an emerging virus from the Flaviviridae family and Flavivirus genus that has caused important outbreaks around the world. ZIKV infection is associated with severe neuropathology in newborns and adults. Until now, there is no licensed vaccine available for ZIKV infection.
Ana Clara, Antonelli +2 more
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Immunoinformatics, Molecular Modeling, and Cancer Vaccines
2014Cancer vaccines are a natural way of fighting the development and progression of cancer as they harness the power of immune system to tweak it into killing cancerous cells. One of the most important agents in an immune system, the cytotoxic T cells (CTL), play a major role and the CTL epitopes in the form of an immunotherapeutic product have been shown
Seema, Mishra, Subrata, Sinha
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Hybrid Neural Networks for Immunoinformatics
International Conference on Computational Intelligence for Modelling, Control and Automation and International Conference on Intelligent Agents, Web Technologies and Internet Commerce (CIMCA-IAWTIC'06), 2006Hybrid set of optimally trained feed-forward, Hop-field and Elman neural networks were used as computational tools and were applied to immunoinformatics. These neural networks enabled a better understanding of the functions and key components of the adaptive immune system.
K.B. Solano, T. Djekovic, M. Zohdy
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Putting immunoinformatics to the test
Nature Biotechnology, 2006A consensus epitope prediction approach identifies the epitopes responsible for 95% of the murine T-cell response to vaccinia virus.
Leonard Moise, Anne S De Groot
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Immunoinformatics: Where Immunology Meets Bioinformatics
Journal of Immunology and Immunopathology, 2019One of the most challenging research areas in biology is to understand the complex immune system and the computational tools have played a pivotal role in increasing the pace of research in the field of immunology. Thus, applications of computational methods and tools in unravelling the complex immune system and thereof translating the understanding in
Naveen Kumar +4 more
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Immunoinformatics and Systems Biology in Personalized Medicine
2014Every year new databases and tools for the storage and analysis of biological data are developed, updated, and discontinued. For this reason it is very important to have a clear picture of the major repositories providing information about the availability of these databases and tools as well as a brief description of them.
Guillermo, Lopez-Campos +3 more
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