Pathophysiology of Congenital High Production of IgE and Its Consequences: A Narrative Review Uncovering a Neglected Setting of Disorders. [PDF]
Galletta F+7 more
europepmc +1 more source
Abstract A reduced proportion of peripheral class‐switched memory B cells (CSM‐B cells) is presumed to indicate ineffective germinal activity. The extent that this finding corresponds to a plausible germinal center failure pathophysiology in patients not diagnosed with CVID or hyper IgM syndrome is not known.
Vijaya Knight+3 more
wiley +1 more source
Clinical and immunological features of specific antibody deficiency in a pediatric hospital in Colombia [PDF]
Castaño-Jaramillo LM+5 more
europepmc +1 more source
Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher+3 more
wiley +1 more source
Quantifying the Diagnostic Odyssey Burden Among Persons with Inborn Errors of Immunity. [PDF]
Nikzad S+3 more
europepmc +1 more source
Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets
Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley +1 more source
Comorbidities in hidradenitis suppurativa: Role of metabolic syndrome and sexual dysfunction disorders in postoperative healing. [PDF]
Ravi S+5 more
europepmc +1 more source
Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna+4 more
wiley +1 more source
Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine. [PDF]
Esmailian A, Barnes SL, Pumar M.
europepmc +1 more source
Immunodeficiency: Overview of primary immune regulatory disorders (PIRDs). [PDF]
Nelson CS, Baloh CH.
europepmc +1 more source