Results 81 to 90 of about 5,981,210 (344)
Defining the South African Acute Respiratory Infectious Disease Season
, 2023 The acute respiratory infectious disease season, or colloquially the “flu season”, is defined as the annually recurring period characterized by the prevalence of an outbreak of acute respiratory infectious diseases.
Neville Sweijd +2 more
core +1 more source
Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19
JCI Insight, 2023 BACKGROUND After its introduction as standard-of-care for severe COVID-19, dexamethasone has been administered to a large number of patients globally.
Charlotte Thibeault +20 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Guns, germs, and stealing: exploring the link between infectious disease and crime. [PDF]
, 2013 Can variation in crime rates be traced to the threat of infectious disease? Pathogens pose an ongoing challenge to survival, leading humans to adapt defenses to manage this threat.
Ilan Shrira +5 more
core +1 more source
Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease
JCI Insight, 2021 In this study, we examined and characterized disease-specific TCR signatures in cerebrospinal fluid (CSF) of patients with HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Satoshi Nozuma +8 more
doaj +1 more source
Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
Frontiers in Immunology, 2014 The evolution of macrophages has made them primordial for both development and immunity. Their functions range from the shaping of body plans to the ingestion and elimination of apoptotic cells and pathogens.
Guillermo Arango Duque, A. Descoteaux
semanticscholar +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
JCI Insight, 2022 Understanding the immune response to dengue virus (DENV) is essential for developing a dengue vaccine that is protective against all 4 DENV serotypes. We evaluated the immune response after vaccination (live attenuated tetravalent dengue vaccine TV005 or
Ruixue Hou +7 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Life histories offer a clue to the future role of infectious disease in coral reefs [PDF]
, 2012 Increased frequency and severity of stressors associated with climate change are drastically altering ecosystems. Caribbean coral reefs differ markedly from just 30 years ago, with much restructuring attributable to infectious disease outbreaks.
Mumby, P. J. +5 more
core +1 more source