ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Hereditary alpha-tryptasemia demonstrates relative basophil enrichment without signs of cellular hyperreactivity. [PDF]
Johnsson AK +3 more
europepmc +1 more source
ABSTRACT Renal impairment (RI), defined as estimated glomerular filtration rate less than 60 mL/min with or without the need for dialysis, is a frequent and severe complication in patients with relapsed/refractory multiple myeloma (RRMM), as it can affect patient prognosis, drug metabolism and treatment options.
Ioannis Ntanasis‐Stathopoulos +7 more
wiley +1 more source
IgE-mediated cocoa allergy: a pediatric case report and review of the literature. [PDF]
Sarti L +11 more
europepmc +1 more source
A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger +14 more
wiley +1 more source
FoodCHOMP (Food Challenge-at HOme or in Medical Practice): a pilot multicentre randomised controlled trial evaluating home versus clinic-based food allergy challenges in low-risk adults-study protocol. [PDF]
Godsell J +8 more
europepmc +1 more source
World Allergy Organization survey on the diagnosis and management trends of perioperative anaphylaxis. [PDF]
Gonzalez-Estrada A +19 more
europepmc +1 more source
Maternal characteristics associated with ovalbumin concentrations in breast milk. [PDF]
Hughes SA +4 more
europepmc +1 more source
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source

