Results 161 to 170 of about 1,214,228 (245)

Post-marketing safety of immunomodulatory drugs in multiple myeloma: A pharmacovigilance investigation based on the FDA adverse event reporting system. [PDF]

Front Pharmacol, 2022
Jiang T, Su H, Li Y, Wu Y, Ming Y, Li C, Fu R, Feng L, Li Z, Li L, Ni R, Liu Y.   +11 more
europepmc   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

Advanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu, Xiaodong Luo, Jingxian Wu, Chaoyang Huang, Zhuoying Yang, Yixiang HePeng, Bosong Zhou, Xiang Li, Ruiyuan Liu, Xu Wu   +9 more
wiley   +1 more source

Differential treatment effects across subgroups in immunomodulatory drugs for sepsis: protocol for a systematic review. [PDF]

BMJ Open
Ding L, Bai C, Jian L, Hu D, Xiong J, Zhang Z, He Q, Wang Y, Xu J, Ge L, Wang W, Sun X.   +11 more
europepmc   +1 more source

Analysis of humoral and cellular immunity after SARS-CoV-2 vaccination in patients with multiple sclerosis treated with immunomodulatory drugs. [PDF]

Clin Immunol Commun, 2023
Meca-Lallana V, Esparcia-Pinedo L, Aguirre C, Díaz-Pérez C, Gutierrez-Cobos A, Sobrado M, Carabajal E, Río BD, Ropero N, Villagrasa R, Vivancos J, Sanchez-Madrid F, Alfranca A.   +12 more
europepmc   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Peripheral Neuropathy Associated With Proteasome Inhibitors and Immunomodulatory Drugs: A Pharmacovigilance Disproportionality Analysis Using VigiBase. [PDF]

Pharmacol Res Perspect
Braga LP, de Pádua CAM, da Costa IHF, de Miranda Drummond PL, de Souza PHC, Fonseca LB, Rodrigues MA, Malta JS, Reis AMM.   +8 more
europepmc   +1 more source

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma. [PDF]

Oncotarget, 2021
Thakurta A, Pierceall WE, Amatangelo MD, Flynt E, Agarwal A.   +4 more
europepmc   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

Advanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang, Xinyu Ren, Dalin Ma, Hao Pang, Wei Chen, Kaize Cai, Mei Yuan, Bingzhi Zhang, Zufang Lin, Xiaoshuai Liu   +9 more
wiley   +1 more source

Identification of Drug Repurposing Opportunities of Immunomodulatory Drugs for Inflammatory Bowel Disease Through Inverse Pharmacovigilance Signal Detection in the FAERS Database. [PDF]

J Clin Med
Đogatović K, Vučićević K, Kovačević M, Ćulafić M, Miljković B, Kovačević SV.   +5 more
europepmc   +1 more source

Bridging Therapies With Injectable Immunomodulatory Drugs in the Management of Multiple Sclerosis: A Delphi Survey of an Italian Expert Panel of Neurologists. [PDF]

Front Neurol, 2022
Marfia GA, Centonze D, Salvetti M, Ferraro E, Panetta V, Gasperini C, Mirabella M, Conte A.   +7 more
europepmc   +1 more source