Results 1 to 10 of about 180,494 (192)

Longitudinal changes in serum soluble C5b-9 levels following immunomodulatory therapy for multisystem inflammatory syndrome in children [PDF]

Clinical and Experimental Pediatrics
Background Multisystem inflammatory syndrome in children (MIS-C) is a postinfectious hyperinflammatory condition that can follow a sudden acute respiratory syndrome coronavirus 2 infection.
Amrita Pattanaik, Prasad Varamballi, Srilatha Marate, Sushma Bhandarkar B., Shrikiran Aroor, Somashekar A.R., Suchetha S. Rao, Chiranjay Mukhopadhyay   +7 more
doaj   +2 more sources

Effects of Immunomodulatory Therapy on the Skin Barrier Function in Patients with Psoriasis Vulgaris [PDF]

Medicina
Background and Objectives: Psoriasis vulgaris features epidermal barrier dysfunction. Materials and Methods: Barrier function changes were prospectively evaluated over 12 weeks during TNF-α inhibition with adalimumab, along with concurrent changes in ...
Anete Mālkalne, Vanda Bondare-Ansberga, Ilona Hartmane, Ingmārs Mikažāns, Lelde Reinberga   +4 more
doaj   +2 more sources

Thymosin alpha1 based immunomodulatory therapy for sepsis: a systematic review and meta-analysis

International Journal of Infectious Diseases, 2015
Objectives: Thymosin alpha1 (Tα1) is considered a promising immunomodulatory drug. However, it is still unclear whether Tα1 should be recommended for the management of sepsis. Here we conducted a systematic review and meta-analysis to assess the efficacy
Congcong Li, Liyan Bo, Qingqing Liu, Faguang Jin   +3 more
doaj   +3 more sources

Real-Life Experience with Pomalidomide plus Low-Dose Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma: A Retrospective and Prospective Study

Medicina, 2021
Background and Objectives: The treatment of Myeloma after the second relapse is still challenging. The aim of the study was to investigate the outcomes of the POM-DEX regimen in real clinical practice.
Maria Livia Del Giudice, Alessandro Gozzetti, Elisabetta Antonioli, Enrico Orciuolo, Francesco Ghio, Sara Ciofini, Veronica Candi, Giulia Fontanelli, Irene Attucci, Giuseppe Formica, Monica Bocchia, Sara Galimberti, Mario Petrini, Gabriele Buda   +13 more
doaj   +1 more source

The real‐world use and efficacy of pomalidomide for relapsed and refractory multiple myeloma in the era of CD38 antibodies

eJHaem, 2023
Pomalidomide‐dexamethasone (Pd) has been a standard care treatment for relapsed and refractory multiple myeloma since 2013. However, the outcomes of Pd after exposure to CD38 antibodies are not known.
Agoston Gyula Szabo, Jonathan Thorsen, Katrine Fladeland Iversen, Mette Bøegh Levring, Carsten Helleberg, Emil Hermansen, Søren Thorgaard Bønløkke, Katrine Nielsen, Elena Manuela Teodorescu, Eva Kurt, Casper Nørgaard Strandholdt, Annette Juul Vangsted   +11 more
doaj   +1 more source

In dogs with atopic skin disease, is lokivetmab more effective than oclacitinib in reducing the score of a recognised scoring system?

Veterinary Evidence, 2022
PICO question In dogs with atopic skin disease, is lokivetmab more effective than oclacitinib in reducing the Canine Atopic Dermatitis Lesion Index score (or some other recognised scoring system)?
Bonnie Yuan Tone Cheung
doaj   +1 more source

Treatment Approaches for Atypical CIDP

Frontiers in Neurology, 2021
The variants of chronic inflammatory demyelinating polyneuropathy (CIDP) differ not just in their clinical, pathological and electrophysiological characteristics, but often in their indifferent response to conventional immunosuppressive agents which are ...
Deepak Menon, Hans Dieter Katzberg, Vera Bril   +2 more
doaj   +1 more source

Multiple sclerosis and COVID-19

Biomedical Papers, 2020
This paper reviews currently available data on the novel coronavirus and clinical features of COVID-19, followed by a detailed section on possible modifications of immunomodulatory therapy in multiple sclerosis patients with COVID-19, based on what we ...
Jan Mares, Hans-Peter Hartung
doaj   +1 more source

Clinical and immunological efficacy of immunotherapeutic program after surgical treatment of children with various forms of acute peritonitis

Медицинская иммунология, 2022
Acute peritonitis (AP) is among the most frequent and severe conditions in pediatric abdominal surgery. Due to development of antibiotic resistance and increasing number of atypical infectious and inflammatory diseases (IIDs), a lot of specialists ...
I. V. Nesterova, G. A. Chudilova, V. N. Chapurina, S. V. Kovaleva, Yu. V. Teterin, N. K. Barova, D. E. Lyagusha, V. A. Tarakanov   +7 more
doaj   +1 more source

Immunomodulatory Therapy for Rasmussen Syndrome

Pediatric Neurology Briefs, 2013
Investigators from the National Epilepsy Center, Shizuoka, Gifu University, Tokyo Women’s Medical University, National Center of Neurology and Psychiatry, and Okayama University School of Medicine, Japan, examined seizure, cognitive, and motor outcomes ...
J Gordon Millichap
doaj   +1 more source