Results 1 to 10 of about 39,466 (197)

Immunophenotyping beyond the limits of time

Cell Reports Methods, 2023
Immunophenotyping is a powerful approach for deciphering responses of the immune system to drug screening and immunotherapy. In this issue of Cell Report Methods, Liechti et al. have advanced this approach by developing a pipeline, which allows high-throughput but still accurate single-cell immunophenotyping in time.
J. Fréderique de Graaf, Ramon Arens
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Immunophenotyping of Tumours [PDF]

Medical Journal Armed Forces India, 2008
Immunophenotyping has added a new dimension to improve the diagnostic accuracy of malignant diseases. The emphasis is on its usefulness in planning and institution of specific therapy besides helping in prognostication.The study included 83/1385 biopsies of cancer patients over an 18 month period on which immunohistochemical staining (IHC) with ...
Ritu Lakhtakia, S K Nema
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Immunophenotyping of congenital leukemia [PDF]

Cytometry, 1995
AbstractCongenital leukemia is a rare but well‐documented disease in which a leukemic process is detected at birth or very shortly thereafter. An estimated 175–200 reports of congenital leukemia have appeared in the literature. The majority of the cases reported have not undergone thorough immunophenotyping, but rather have been assigned lineage based ...
Overton Wr, McCoy Jp
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Microglia immunophenotyping in gliomas

Oncology Letters, 2017
Microglia, once assimilated to peripheral macrophages, in gliomas has long been discussed and currently it is hypothesized to play a pro-tumor role in tumor progression. Uncertain between M1 and M2 polarization, it exchanges signals with glioma cells to create an immunosuppressive microenvironment and stimulates cell proliferation and migration.
Bianca Pollo, Enrica Bovio, Laura Annovazzi, S. Mazzetti, Marta Mellai, Davide Schiffer   +5 more
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Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium [PDF]

Scientific Reports, 2016
AbstractStandardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-color panels for identification of major immune cell subsets in peripheral blood.
Greg Finak, Aaron Brandes, John A. Ramey, Elaine F. Reed, Florian Kern, Karolina Palucka, Jafar Taghiyar, Raphael Gottardo, Tim R. Mosmann, Tim R. Mosmann, Mehrnoush Malek, Susanne Heck, Lesley Devine, Kui Wang, J. Philip McCoy, Nadia Terrazzini, Federica Villanova, Gerlinde Obermoser, Yael Korin, Ryan R. Brinkman, Ryan R. Brinkman, Bonnie B. Blomberg, Khadir Raddassi, Frank Nestle, Rick Stanton, Holden T. Maecker, Virginia Pascual, Yu Qian, Nikolas Pontikos, Maria Jaimes, Richard H. Scheuermann, Robert B. Nussenblatt, Marc Langweiler, Nima Aghaeepour, Nima Aghaeepour, Alain Diaz, Marcin L. Pekalski   +36 more
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Immunophenotyping of pulmonary sarcomatoid carcinoma

Frontiers in Immunology, 2022
BackgroundPrevious studies have suggested that patients with pulmonary sarcomatoid carcinoma (PSC)may benefit from immune checkpoint inhibitors (ICIs); however, relevant data are lacking. This study aimed to establish the immunophenotype of PSC by assessing PD-L1 and CD8+ T-cell infiltration.MethodsA retrospective analysis of pathologically confirmed ...
Yu Ma, Wensheng Li, Zhenzhen Li, Jie Chen, Hongtao Wang, Tao Jiang, Jianfei Zhu   +6 more
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T-LYMPHOCYTE IMMUNOPHENOTYPING IN POLYMYOSITIS AND DERMATOMYOSITIS [PDF]

Rheumatology, 1996
The objective was to elucidate the immunological abnormalities underlying polymyositis (PM) and dermatomyositis (DM). The phenotype of peripheral blood mononuclear cell (PBMNC) subsets and cell surface expression of activation (CD25 and HLA-DR) and adhesion (LFA-1) molecules was studied in 12 patients with PM and in 10 patients with DM.
Iannone F, CAULI, ALBERTO, Yanni G, Kingsley GH, Isenberg DA, Corrigall V, Panayi GS   +6 more
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Immunophenotype Heterogeneity in Nasal Glomangiopericytoma [PDF]

Case Reports in Otolaryngology, 2015
Nasal glomangiopericytoma is rare. The immunophenotype is heterogeneous, more frequently smooth-muscle-actin and CD34-positive. We report expression patterns for several vascular-related proteins such as CD99, CD146, Bcl2, and WT1 as well as for treatment-related proteins such as mTOR and EGFR in a nasal glomangiopericytoma.
Marick Laé, Adriana Handra-Luca, Christina Magkou, Zakaria Y. Abd Elmageed   +3 more
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The immunophenotype of osteoclasts and macrophage polykaryons

Journal of Clinical Pathology, 2011
AimOsteoclasts are multinucleated cells which are specialised to carry out lacunar bone resorption. Osteoclasts form part of the mononuclear phagocyte system, and immunophenotypic criteria for distinction from macrophage polykaryons include expression of CD51 (vitronectin receptor) and absence of HLA-DR and CD14.MethodsThe expression of CD14, CD163 ...
Maggiani, F., Forsyth, R., Hogendoorn, P.C.W., Krenacs, T., Athanasou, N.A.   +4 more
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Immunophenotypic dissection of normal hematopoiesis

Journal of Immunological Methods, 2019
Flow cytometry immunophenotyping is essential for diagnosis, classification and monitoring of clonal hematopoietic diseases, particularly of hematological malignancies and primary immunodeficiencies. Optimal use of immunophenotyping for these purposes requires detailed knowledge about the phenotypic patterns of normal hematopoietic cells.
Orfao, A., Matarraz, S., Perez-Andres, M., Almeida, J., Teodosio, C., Berkowska, M.A., Dongen, J.J.M. van, EuroFlow   +7 more
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