Results 1 to 10 of about 84,555 (389)

Application and interpretation of immunophenotyping data in safety and risk assessment [PDF]

Frontiers in Toxicology
The use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments.
Victor J. Johnson, Michael I. Luster, Andrew Maier, Andrew Maier, Corey Boles, Corey Boles, Eric W. Miller, Daniel E. Arrieta   +7 more
doaj   +2 more sources

Immunophenotyping of pulmonary sarcomatoid carcinoma

Frontiers in Immunology, 2022
Background Previous studies have suggested that patients with pulmonary sarcomatoid carcinoma (PSC)may benefit from immune checkpoint inhibitors (ICIs); however, relevant data are lacking.
Yu Ma, Wensheng Li, Zhenzhen Li, Jie-Fu Chen, Hongtao Wang, Tao Jiang, Jianfei Zhu   +6 more
semanticscholar   +4 more sources

Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International Prognostic Index (IPI) [PDF]

Journal of Hematology & Oncology, 2009
Background The International Prognostic Index (IPI) is used to determine prognosis in diffuse large B-cell lymphoma (DLBCL). One of the determinants of IPI is the stage of disease with bone marrow involvement being classified as stage IV.
Shadbolt Bruce, Talaulikar Dipti, Dahlstrom Jane E, McDonald Anne   +3 more
doaj   +5 more sources

A Practical Cryopreservation and Staining Protocol for Immunophenotyping in Population Studies [PDF]

Current Protocols in Cytometry, 2018
Large population‐based cohort studies, through their prospective collection of a broad range of health information, represent an invaluable resource for novel insights into the pathogenesis of human diseases.
Barcelo, Helene, Crimmins, Eileen, Faul, Jessica, Thyagarajan, Bharat   +3 more
core   +2 more sources

Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells

Cells, 2022
Carboxypeptidase A3 (CPA3) is a specific mast cell (MC) protease with variable expression. This protease is one of the preformed components of the secretome.
Dmitri Atiakshin, Andrey Kostin, Ivan Trotsenko, Vera Samoilova, Igor Buchwalow, Markus Tiemann   +5 more
doaj   +1 more source

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect

Pharmaceuticals, 2023
The mechanisms of regeneration for the fibrous component of the connective tissue of the dermis are still insufficiently studied. The aim of this study was to evaluate the effectiveness of the use of molecular hydrogen on the local therapy of a II degree
Dmitri Atiakshin, Mariya Soboleva, Dmitry Nikityuk, Nataliya Alexeeva, Svetlana Klochkova, Andrey Kostin, Viktoriya Shishkina, Igor Buchwalow, Markus Tiemann   +8 more
doaj   +1 more source

Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment

Pharmaceuticals, 2023
Knowledge of the biological effects of molecular hydrogen (H2), hydrogen gas, is constantly advancing, giving a reason for the optimism in several healthcare practitioners regarding the management of multiple diseases, including socially significant ones
Dmitri Atiakshin, Andrey Kostin, Artem Volodkin, Anna Nazarova, Viktoriya Shishkina, Dmitry Esaulenko, Igor Buchwalow, Markus Tiemann, Mami Noda   +8 more
doaj   +1 more source

Prognostic Immunophenotyping Clusters of Clear Cell Renal Cell Carcinoma Defined by the Unique Tumor Immune Microenvironment

Frontiers in Cell and Developmental Biology, 2021
Background: The tumor microenvironment affects the occurrence and development of cancers, including clear cell renal cell carcinoma (ccRCC). However, how the immune contexture interacts with the cancer phenotype remains unclear.
Wenhao Xu, Aihetaimujiang Anwaier, Chun-guang Ma, Wangrui Liu, X. Tian, Jia-Qi Su, Wenkai Zhu, Guohai Shi, Shiyin Wei, Hong Xu, Y. Qu, D. Ye, Hailiang Zhang   +12 more
semanticscholar   +1 more source

Lymphocyte immunophenotyping in inflammatory myositis: a review

Current Opinion in Rheumatology, 2021
Purpose of review This is a comprehensive review of the current knowledge on predominant immune cell phenotypes involved in idiopathic inflammatory myopathies (IIM).
C. Franco, M. Gatto, L. Iaccarino, A. Ghirardello, A. Doria   +4 more
semanticscholar   +1 more source

The Use of CD200 in the Differential Diagnosis of B-Cell Lymphoproliferative Disorders

British Journal of Biomedical Science, 2023
Background: B-Cell Lymphoproliferative Disorders (B-LPDs) are a group of heterogenous disorders characterised by the accumulation of B-cells in peripheral blood, bone marrow, lymph nodes and spleen.
Hanaan Kareem Al-Zubaidi, Stephen Fôn Hughes   +1 more
doaj   +1 more source