Results 1 to 10 of about 70,782 (340)

Immunophenotyping of pulmonary sarcomatoid carcinoma

Frontiers in Immunology, 2022
Background Previous studies have suggested that patients with pulmonary sarcomatoid carcinoma (PSC)may benefit from immune checkpoint inhibitors (ICIs); however, relevant data are lacking.
Yu Ma, Wensheng Li, Zhenzhen Li, Jie-Fu Chen, Hongtao Wang, Tao Jiang, Jianfei Zhu   +6 more
semanticscholar   +4 more sources

Advanced immunophenotyping: A powerful tool for immune profiling, drug screening, and a personalized treatment approach

Frontiers in Immunology, 2023
Various autoimmune diseases are characterized by distinct cell subset distributions and activation profiles of peripheral blood mononuclear cells (PBMCs). PBMCs can therefore serve as an ideal biomarker material, which is easily accessible and allows for
Teresa Preglej, Marie Brinkmann, Günter Steiner, Daniel Aletaha, Lisa Göschl, Michael Bonelli   +5 more
doaj   +2 more sources

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium [PDF]

Scientific Reports, 2016
Standardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-
Greg Finak, M. Langweiler, M. Jaimes, Mehrnoush Malek, Jafar Taghiyar, Y. Korin, K. Raddassi, L. Devine, G. Obermoser, M. Pekalski, N. Pontikos, A. Díaz, S. Heck, F. Villanova, N. Terrazzini, F. Kern, Y. Qian, Rick Stanton, Kui Wang, Aaron Brandes, John Ramey, N. Aghaeepour, T. Mosmann, T. Mosmann, R. Scheuermann, E. Reed, K. Palucka, V. Pascual, B. Blomberg, F. Nestle, R. Nussenblatt, R. Brinkman, R. Gottardo, H. Maecker, J. P. Mccoy   +34 more
semanticscholar   +5 more sources

Immunophenotyping beyond the limits of time

Cell Reports: Methods, 2023
Immunophenotyping is a powerful approach for deciphering responses of the immune system to drug screening and immunotherapy. In this issue of Cell Report Methods, Liechti et al.
J. Fréderique de Graaf, Ramon Arens
doaj   +3 more sources

Microglia immunophenotyping in gliomas

Oncology Letters, 2017
Microglia, once assimilated to peripheral macrophages, in gliomas has long been discussed and currently it is hypothesized to play a pro-tumor role in tumor progression.
L. Annovazzi, M. Mellai, Enrica Bovio, S. Mazzetti, B. Pollo, D. Schiffer   +5 more
semanticscholar   +5 more sources

Application and interpretation of immunophenotyping data in safety and risk assessment [PDF]

Frontiers in Toxicology
The use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments.
Victor J. Johnson, Michael I. Luster, Andrew Maier, Andrew Maier, Corey Boles, Corey Boles, Eric W. Miller, Daniel E. Arrieta   +7 more
doaj   +2 more sources

Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells

Cells, 2022
Carboxypeptidase A3 (CPA3) is a specific mast cell (MC) protease with variable expression. This protease is one of the preformed components of the secretome.
Dmitri Atiakshin, Andrey Kostin, Ivan Trotsenko, Vera Samoilova, Igor Buchwalow, Markus Tiemann   +5 more
doaj   +1 more source

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect

Pharmaceuticals, 2023
The mechanisms of regeneration for the fibrous component of the connective tissue of the dermis are still insufficiently studied. The aim of this study was to evaluate the effectiveness of the use of molecular hydrogen on the local therapy of a II degree
Dmitri Atiakshin, Mariya Soboleva, Dmitry Nikityuk, Nataliya Alexeeva, Svetlana Klochkova, Andrey Kostin, Viktoriya Shishkina, Igor Buchwalow, Markus Tiemann   +8 more
doaj   +1 more source

Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment

Pharmaceuticals, 2023
Knowledge of the biological effects of molecular hydrogen (H2), hydrogen gas, is constantly advancing, giving a reason for the optimism in several healthcare practitioners regarding the management of multiple diseases, including socially significant ones
Dmitri Atiakshin, Andrey Kostin, Artem Volodkin, Anna Nazarova, Viktoriya Shishkina, Dmitry Esaulenko, Igor Buchwalow, Markus Tiemann, Mami Noda   +8 more
doaj   +1 more source

Prognostic Immunophenotyping Clusters of Clear Cell Renal Cell Carcinoma Defined by the Unique Tumor Immune Microenvironment

Frontiers in Cell and Developmental Biology, 2021
Background: The tumor microenvironment affects the occurrence and development of cancers, including clear cell renal cell carcinoma (ccRCC). However, how the immune contexture interacts with the cancer phenotype remains unclear.
Wenhao Xu, Aihetaimujiang Anwaier, Chun-guang Ma, Wangrui Liu, X. Tian, Jia-Qi Su, Wenkai Zhu, Guohai Shi, Shiyin Wei, Hong Xu, Y. Qu, D. Ye, Hailiang Zhang   +12 more
semanticscholar   +1 more source