Results 121 to 130 of about 97,573 (376)

Chronic lymphocytic leukemia in Kenya: an immunophenotypic and clinicopathologic study [PDF]

, 2013
Objective: To define cases of chronic lymphocytic leukemia (CLL) by immunophenotypic criteria and describe the associated clinical features in patients diagnosed at Aga Khan University Hospital, Nairobi. Background: Rising to the growing cancer challenge
Mulwa-Babu, E., Paresh, D., Riyat, M.
core   +2 more sources

Single‐Cell Profiling: Any Scale, Any Size, All at Once

Advanced Science, EarlyView.
Traditional single‐cell technologies are constrained by cellular dimension and throughput scale, in addition to its inability preserve spatial information. With recent innovations, these technologies now allow high throughput, large‐sized cell, and multi‐modal profiling of patient samples, overcoming these limitations.
Denise Goh, Felicia Wee, Rachel Elizabeth Ann Fincham, Ruisi Li, Joe Yeong   +4 more
wiley   +1 more source

Why not "do simple things in a simple way": Use of the Pap test as the first step in screening genetic stability for human cultured stem cell therapy? [PDF]

, 2011
The aim of this study was to analyze adipose tissue-derived mesenchymal stem cells (AT-MSCs) using the Pap test as a first screening step to evaluate genetic stability.
Ana Carolina Irioda, Carolina Maria Costa de Oliveira Souza, Diogo Kuczera, Eduardo Aliprandini, Julio C Francisco, Katherine Athayde Teixeira de Carvalho, Larissa Zocche, Lismary Mesquita, Luiz Cesar Guarita-Souza, Mariester Malvezzi, Miriam Beltrame, Rafael Vargas, Reginaldo J. Ferreira, Ricardo C Cunha   +13 more
core   +1 more source

Acute myeloid leukemia with RAM immunophenotype presenting with extensive mesenteric and retroperitoneal lymphadenopathy: A case report and review of the literature

, 2021
Neda Wick, I Hitto, D Welder, Tamra Slone, Prasad Koduru, Frankling Fuda, Dinesh Rakheja, Olga K. Weinberg   +7 more
openalex   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) [PDF]

, 2017
Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands.
De Los Monteros, A E, Grau-Bassas, E R, Herráez, P, Priestnall, S L, Quesada-Canales, O, Suárez-Bonnet, A   +5 more
core   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Development of a Modular Assay for Detailed Immunophenotyping of Peripheral Human Whole Blood Samples by Multicolor Flow Cytometry

International Journal of Molecular Sciences, 2016
The monitoring of immune cells gained great significance in prognosis and prediction of therapy responses. For analyzing blood samples, the multicolor flow cytometry has become the method of choice as it combines high specificity on single cell level ...
P. Rühle, R. Fietkau, U. Gaipl, B. Frey
semanticscholar   +1 more source

Table S1 from TIP: A Web Server for Resolving Tumor Immunophenotype Profiling

, 2023
Liwen Xu, Chunyu Deng, Bo Pang, Xinxin Zhang, Wei Liu, Gaoming Liao, Huating Yuan, Cheng Peng, Feng Li, Zhilin Long, Min Yan, Tingting Zhao, Yun Xiao, Xia Li   +13 more
openalex   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source