Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. [PDF]
Background/objectivesThe common non-coding single nucleotide polymorphism (SNP) rs3129882 in HLA-DRA is associated with risk for idiopathic Parkinson's disease (PD).
Boss, JM +11 more
core +2 more sources
Panel Optimization for High‐Dimensional Immunophenotyping Assays Using Full‐Spectrum Flow Cytometry
Laura Ferrer‐Font +8 more
openalex +1 more source
ABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) for large superficial non‐ampullary duodenal epithelial tumors (SNADETs) poses substantial technical challenges, primarily because of a heightened risk of adverse events (AEs). Laparoscopic and endoscopic cooperative surgery (D‐LECS) was introduced to address these risks, with recent ...
Masaru Hayami +9 more
wiley +1 more source
Disentangling Coincident Cell Events Using Deep Transfer Learning and Compressive Sensing
Overlapping cells during detection distort single‐cell measurements and reduce diagnostic accuracy. A hybrid framework combining a fully convolutional neural network with compressive sensing to disentangle overlapping signals directly from raw time‐series data is presented.
Moritz Leuthner +2 more
wiley +1 more source
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that leads to destructive arthritis. Although the HLA class II locus is the strongest genetic risk factor for rheumatoid arthritis, the relationship between HLA class II alleles and ...
Y. Nagafuchi +16 more
semanticscholar +1 more source
OMIP ‐ 081: A new 21‐monoclonal antibody 10‐color panel for diagnostic polychromatic immunophenotyping [PDF]
Erik Huys +2 more
openalex +1 more source
Here, we present RanBALL, an ensemble random projection‐based model for accurate and cost‐effective identification of B‐cell acute lymphoblastic leukemia subtypes is presented. By preserving patient‐to‐patient distance after dimension reduction by random projection and ensemble learning, RanBALL can facilitate the discovery of B‐ALL subtype‐specific ...
Lusheng Li +6 more
wiley +1 more source
LARGE EXTRANODAL NON HODGKIN'S LYMPHOMA OF THE PARAPHARYNGEAL SPACE [PDF]
Of all head and neck tumors, 0.5% to 0.8% of them are localized in the parapharyngeal space. Non-Hodgkin’s lymphomas in this site are extremely rare. There are described in literature as either isolated cases or small series of tumors of that space.
Aleric, Zorica, Bauer, Vladimir
core +1 more source
In-depth immunophenotyping with mass cytometry during TB treatment reveals non-canonical T-cell subsets associated with sputum culture conversion [PDF]
Carole Chedid +15 more
openalex +1 more source
Extramedullary Disease—Achilles Heel in Myeloma?
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar +7 more
wiley +1 more source

