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Immunophenotyping of acute leukaemias
Immunology Letters, 2005Progress in the management and understanding of acute leukaemia can only be obtained if these diseases are thoroughly investigated, both clinically and with a series of biological tools. This alone has made and still will make possible the identification of prognostic factors and of useful markers for the follow-up of patients in remission.
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The immunophenotype of pituitary adenomas
Endocrine Pathology, 1996Although the production of pituitary hormones by adenohypophysial tumors has been studied extensively, an examination of the immunophenotype of pituitary adenomas using a broad spectrum of antibodies has not been previously investigated. We studied 23 pituitary adenomas using a large panel of antibodies to determine if these tumors exhibited a common ...
Ricardo V. Lloyd +3 more
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Immunophenotype of Myxopapillary Ependymomas
Applied Immunohistochemistry & Molecular Morphology, 2013Myxopapillary ependymoma (MPE) is a slow-growing tumor occurring almost exclusively in the region of conus medullaris, cauda equina, and filum terminale. On microscopic examination, some of these tumors show solid sheets of cells with an epithelioid morphology mimicking a metastatic carcinoma.
Paolo Gattuso +4 more
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Immunophenotyping of aneuploid cells
Cancer Genetics and Cytogenetics, 1989This review article describes the MAC and MACISH (morphology, antibody, chromosomes, in situ hybridization) methods, which allow the examination of numerical chromosome abnormalities of morphologically and immunologically classified interphase or mitotic cells.
Lasse Teerenhovi, Sakari Knuutila
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Immunophenotypical Changes of T Lymphocytes in the Elderly
Gerontology, 2000<i>Background:</i> Substantial changes in both representation and function of T lymphocyte subsets have been reported with advancing age. However, till now, no systematic studies focused on age-dependent changes in the expression intensity of the major T lymphocyte surface receptors.
GINALDI, Lia +5 more
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Immunophenotyping of Plasma Cells
Current Protocols in Cytometry, 2006AbstractPlasma cell enumeration and immunophenotyping has been shown to be of value in predicting the outcome for patients with myeloma. Detection of abnormal plasma cells at a leukocyte level >0.01% at the end of therapy predicts early relapse. Although clonally related populations at varying stages of differentiation are reported to be present in ...
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Immunophenotyping as a guide for targeted therapy
Best Practice & Research Clinical Haematology, 2003Immunophenotyping of acute and chronic leukaemias has revealed many lineage- and differentiation-specific antigens. It has now become possible to classify leukaemias according to their unique antigenic expression pattern. Among many lineage- and differentiation-specific antigens, disease-specific antigens are increasingly recognized because of their ...
Pieter Sonneveld, Rob Pieters
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2004
Publisher Summary B-lymphocytes provide the humoral (antibody-mediated) arm of the adaptive immune system. Like all leukocytes, B cells develop from hematopoietic stem cells in the bone marrow. The bone marrow is a tissue where B cells of all developmental stages can be isolated.
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Publisher Summary B-lymphocytes provide the humoral (antibody-mediated) arm of the adaptive immune system. Like all leukocytes, B cells develop from hematopoietic stem cells in the bone marrow. The bone marrow is a tissue where B cells of all developmental stages can be isolated.
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Fluorescent Cell Barcoding for Immunophenotyping
2019Immunophenotyping using flow cytometry highly benefits from multiplexing samples for generation of more robust data, because of reduction of antibody consumption, batch effect and technical variations. One way to multiplex is via fluorescent cell barcoding (FCB) prior to staining procedure.FCB is a high-throughput multiplexed assay using various ...
Giudice V., Fantoni G., Biancotto A.
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Immunophenotypic Analysis of Acute Leukemia
American Journal of Clinical Pathology, 1993Since the introduction of monoclonal antibodies for the study of hematopoietic disease in the early 1980s, techniques to aid in the identification of cell lineage have proliferated. Immunofluorescent flow-cytometric studies are particularly helpful in the characterization of acute leukemia, and when used in conjunction with light-microscopic findings ...
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