Results 41 to 50 of about 63,836 (336)

Evaluation of human umbilical cord blood as a source of embryonic stem cells [PDF]

, 2013
Human umbilical cord blood (HUCB) has been poorly characterised as a source of embryonic stem cells (ESCs). The aim of this study, therefore, was to evaluate HUCB as source of mesenchymal stem cells (MSCs) with embryonic characteristics.
El-Sheemy, Mohamed, Eremin, Oleg, Hussain, Issam, Magd, Salah A.   +3 more
core   +2 more sources

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium [PDF]

Scientific Reports, 2016
AbstractStandardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-color panels for identification of major immune cell subsets in peripheral blood.
Greg Finak, Aaron Brandes, John A. Ramey, Elaine F. Reed, Florian Kern, Karolina Palucka, Jafar Taghiyar, Raphael Gottardo, Tim R. Mosmann, Tim R. Mosmann, Mehrnoush Malek, Susanne Heck, Lesley Devine, Kui Wang, J. Philip McCoy, Nadia Terrazzini, Federica Villanova, Gerlinde Obermoser, Yael Korin, Ryan R. Brinkman, Ryan R. Brinkman, Bonnie B. Blomberg, Khadir Raddassi, Frank Nestle, Rick Stanton, Holden T. Maecker, Virginia Pascual, Yu Qian, Nikolas Pontikos, Maria Jaimes, Richard H. Scheuermann, Robert B. Nussenblatt, Marc Langweiler, Nima Aghaeepour, Nima Aghaeepour, Alain Diaz, Marcin L. Pekalski   +36 more
openaire   +4 more sources

Peripheral Blood T-lymphocyte Phenotypes in Mother-Child Pairs Stratified by the Maternal HPV Status: Persistent HPV16 vs. HPV-Negative: A Case-Control Study

Viruses, 2022
Only few studies exist on the phenotype distribution of peripheral blood lymphocytes concerning persistent oral HPV infection. T-lymphocyte subsets were phenotyped in women who had persistent genital or oral HPV16 infection, using HPV-negative women as a
Helmi Suominen, Anna Paaso, Hanna-Mari Koskimaa, Seija Grénman, Kari Syrjänen, Stina Syrjänen, Karolina Louvanto   +6 more
doaj   +1 more source

T-LYMPHOCYTE IMMUNOPHENOTYPING IN POLYMYOSITIS AND DERMATOMYOSITIS [PDF]

Rheumatology, 1996
The objective was to elucidate the immunological abnormalities underlying polymyositis (PM) and dermatomyositis (DM). The phenotype of peripheral blood mononuclear cell (PBMNC) subsets and cell surface expression of activation (CD25 and HLA-DR) and adhesion (LFA-1) molecules was studied in 12 patients with PM and in 10 patients with DM.
Iannone F, CAULI, ALBERTO, Yanni G, Kingsley GH, Isenberg DA, Corrigall V, Panayi GS   +6 more
openaire   +3 more sources

Immunophenotyping of pulmonary sarcomatoid carcinoma

Frontiers in Immunology, 2022
BackgroundPrevious studies have suggested that patients with pulmonary sarcomatoid carcinoma (PSC)may benefit from immune checkpoint inhibitors (ICIs); however, relevant data are lacking. This study aimed to establish the immunophenotype of PSC by assessing PD-L1 and CD8+ T-cell infiltration.MethodsA retrospective analysis of pathologically confirmed ...
Yu Ma, Wensheng Li, Zhenzhen Li, Jie Chen, Hongtao Wang, Tao Jiang, Jianfei Zhu   +6 more
openaire   +3 more sources

Hodgkin lymphoma: A clinicopathological and immunophenotypic study

Indian Journal of Medical and Paediatric Oncology, 2016
Introduction: The diagnosis of Hodgkin lymphoma (HL) is defined in terms of its microscopic appearance (histology) and the expression of cell surface markers (immunophenotype).
Kaumudi Konkay, Tara Roshni Paul, Shantveer G Uppin, Digumarti Raghunadha Rao   +3 more
doaj   +1 more source

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia [PDF]

, 2012
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology titled, "ZBTB16-RARA variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature" [1].
Kim, Min Jin, Marschalek, Rolf, Meyer, Claus, Park, Tae Sung, Yang, John Jeongseok   +4 more
core   +1 more source

Application and interpretation of immunophenotyping data in safety and risk assessment

Frontiers in Toxicology
The use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments.
Victor J. Johnson, Michael I. Luster, Andrew Maier, Andrew Maier, Corey Boles, Corey Boles, Eric W. Miller, Daniel E. Arrieta   +7 more
doaj   +1 more source

Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus [PDF]

, 2016
BACKGROUND: Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the underlying molecular mechanisms have not yet been fully elucidated.
ALESSANDRI, cristiano, BARBATI, CRISTIANA, Ciarlo, Laura, COLASANTI, TANIA, CONTI, FABRIZIO, Maselli, Angela, Ortona, Elena, Patrizio, Mario, Pierdominici, Marina, SPINELLI, FRANCESCA ROMANA, VALESINI, Guido, VOMERO, MARTA   +11 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source