Results 11 to 20 of about 5,333 (112)

Sociodemographic Factors, Intent-Uptake Disparities, and Nirsevimab Availability in Infant RSV Immunoprophylaxis [PDF]

Pediatric Reports
Background/Objectives: Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and infant hospitalization in the US. RSV prevention evolved in 2023 as nirsevimab and maternal RSV pre-fusion vaccine became available for healthy ...
Brody J. Lipsett, Benjamin N. Fogel, Katherine E. Shedlock, Ian M. Paul, Eric W. Schaefer, Ruth E. Gardner, Leah D. Kaye, Steven D. Hicks   +7 more
doaj   +2 more sources

Impact of Seasonal Nirsevimab Administration in Infants Born During the RSV Circulation Period on RSV-Related Hospitalizations: A Population-Based Study from Emilia-Romagna, Northern Italy [PDF]

Vaccines
Background: Respiratory syncytial virus (RSV) is a leading cause of hospitalization in early infancy, with the greatest burden occurring in the first months of life. Following the COVID-19 pandemic, many countries experienced intensified RSV circulation.
Susanna Esposito, Matteo Puntoni, Giuseppe Maglietta, Alessandro De Fanti, Chiara Ghizzi, Giacomo Biasucci, Federico Marchetti, Melodie Olivia Aricò, Gianluca Vergine, Marcello Stella, Battista Guidi, Agnese Suppiej, Francesca Alberghi, Emanuele Filice, Maria Elena Capra, Enrico Valletta, Andrea Miceli, Cristina Malaventura, Beatrice Rita Campana, Valentina Fainardi, Caterina Caminiti   +20 more
doaj   +2 more sources

A practical guidance on the prevention and treatment of childhood respiratory syncytial virus infection in Kurdistan [PDF]

Frontiers in Pediatrics
Without an available vaccine in Kurdistan, Respiratory Syncytial Virus (RSV) infection threatens younger children, burdens the healthcare system and contributes to household expenditure on health.
Azad A. Haleem, Azhar Alsaqee, Lana A. Dizayi, Sasan L. Hanna, Abbas A. Rabaty, Serdar Pedawi, Aso F. Salih, Aso F. Salih   +7 more
doaj   +2 more sources

Uptake of combined immunoprophylaxis for newborns exposed to hepatitis B virus in a high hepatitis B endemic rural setting in Northern Ghana [PDF]

BMC Pediatrics
Background Mother-to-Child Transmission (MTCT) is a major route of Hepatitis B Virus (HBV) transmission, accounting for a substantial proportion of new infections, particularly in highly endemic areas.
Okasha Mohammed, Senoo-Dogbey Vivian Efua, Charles Ampong Adjei, Irene Owusu Darkwa, Adiza Atoko Mumuni   +4 more
doaj   +2 more sources

The Impact of Nirsevimab on Bronchiolitis-Related Hospitalizations: A Multicenter Italian Retrospective Comparative Study. [PDF]

Pediatr Pulmonol
ABSTRACT Introduction Bronchiolitis is the leading cause of infant hospitalizations worldwide, primarily driven by respiratory syncytial virus (RSV). Methods This multicenter retrospective comparative study assessed the impact of immunoprophylaxis with nirsevimab against RSV on bronchiolitis‐related hospitalizations in Italy during the 2024–2025 winter
Ghirardo S, Madini B, Ullmann N, Zago A, Ghezzi M, D'Auria E, Minute M, Martelossi S, Vittucci AC, Cristaldi S, Procoli S, Castelletti F, Guaia V, Rocchi A, Andrenacci B, Risso FM, Trombetta A, Barchi L, Foti Randazzese S, Manti S, Gitto E, Mirra V, Siani P, Salvatore Aversa S, De Fanti A, Patria MF, Amaddeo A, Barbi E, Cutrera R.   +28 more
europepmc   +2 more sources

Real-World Effectiveness of Nirsevimab in Preventing RSV Hospitalizations: Evidence of Protection in Southern Italian Infants, 2024-2025. [PDF]

J Med Virol
ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of hospitalization in infants, resulting in millions of cases and hundreds of thousands of deaths worldwide every year. Nirsevimab, a long‐acting monoclonal antibody approved in 2023, has 75%–90% protection against RSV‐related admissions.
Fortunato F, Prato R, Acquafredda A, Campanozzi A, Carri VD, Francavilla R, Iannelli G, Liberatore P, Maffei G, Mariano M, Micelli L, Nesta M, Pastore MR, Calvo A, Rinaldi M, Lopalco PL, Martinelli D.   +16 more
europepmc   +2 more sources

Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice

Frontiers in Immunology, 2021
Complement impacts innate and adaptive immunity. Using a model in which the human KEL glycoprotein is expressed on murine red blood cells (RBCs), we have shown that polyclonal immunoprophylaxis (KELIg) prevents alloimmunization to transfused RBCs when a ...
Vicente Escamilla-Rivera, Manjula Santhanakrishnan, Jingchun Liu, David R. Gibb, James E. Forsmo, James E. Forsmo, Ellen F. Foxman, Ellen F. Foxman, Stephanie C. Eisenbarth, Stephanie C. Eisenbarth, C. John Luckey, James C. Zimring, Krystalyn E. Hudson, Sean R. Stowell, Sean R. Stowell, Jeanne E. Hendrickson, Jeanne E. Hendrickson   +16 more
doaj   +1 more source

Resolution of the independent expert council of the union of experts in the field of immunoprophylaxis

Педиатрическая фармакология, 2023
Профилактика инфекционных заболеваний является одним из приоритетов в сфере охраны здоровья (Федеральный закон от 21 ноября 2011 г. № 323-ФЗ «Об основах охраны здоровья граждан в Российской Федерации» (действующая редакция, 2016 г.).
article Editorial
doaj   +1 more source

HBx 128–133 Deletion Affecting HBV Mother-to-Child Transmission Weakens HBV Replication via Reducing HBx Level and CP/ENII Transcriptional Activity

Viruses, 2022
Some infants born to hepatitis B surface antigen (HBsAg)-positive mothers, especially born to hepatitis B e antigen (HBeAg)-positive mothers, can still be infected with hepatitis B virus (HBV) through mother-to-child transmission (MTCT) of HBV and ...
Yarong Song, Ying Lu, Yi Li, Minmin Liu, Hui Zhuang, Jie Li, Jie Wang   +6 more
doaj   +1 more source

Ranking dynamics of economic burden of infectious diseases as a criterion of effectiveness of epidemiologic control

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
Purpose: rank-based assessment of the economic impact of infectious diseases in the Russian Federation for the further analysis of effectiveness of their prevention and for prioritization of preventive measures.Materials and Methods.
Marina A. Mikheeva, Irina V. Mikheeva
doaj   +1 more source