Advanced Science, EarlyView.This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang +5 more
wiley +1 more source
A solid phase enzyme-linked immunosorbent assay for the antigenic detection of Legionella pneumophila (serogroup 1): A compliment for the space station diagnostic capability [PDF]
It is necessary that an adequate microbiology capability be provided as part of the Health Maintenance Facility (HMF) to support expected microbial disease events and environmental monitoring during long periods of space flight.
Hejtmancik, Kelly E.
core +1 more source
Advanced Science, EarlyView.The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang +12 more
wiley +1 more source
The efficacy of modified Ziehl-Neelsen (MZN) and enzyme linked immunosorbent assay (ELISA) and molecular techniques for detection of cryptosporidia in the stool of gastrointestinal cancer Sudanese patients [PDF]
Dafalla Sidig Mohamed Ali Abdullah +7 more
openalex +1 more source
New paper enzyme-linked immunosorbent technique compared with microimmunofluorescence for detection of human serum antibodies to Rickettsia tsutsugamushi [PDF]
, 1980 John W. Crum +2 more
openalex +1 more source
Advanced Science, EarlyView.A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin +11 more
wiley +1 more source
Visual and supersensitive detection of E. pyrifoliae infection in pear trees through dot enzyme‐linked immunosorbent assay and colloidal gold immunochromatographic strip techniques [PDF]
Nairu Liu +6 more
openalex +1 more source
Advanced Science, EarlyView.This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua +19 more
wiley +1 more source
World Allergy Organization Journal, 2011 Background Grass allergy immunotherapies often consist of a mix of different grass extracts, each containing several proteins of different physiochemical properties; however, the subtle contributions of each protein are difficult to elucidate. This study
Alan Bullimore, BSc +3 more
doaj
Solid-phase immunosorbent technique for rapid detection of Rift Valley fever virus immunoglobulin M by hemagglutination inhibition [PDF]
, 1988 Atef Soliman +2 more
openalex +1 more source