Results 311 to 320 of about 269,737 (365)
Immunosuppressive therapy of asthma [PDF]
Journal of Allergy and Clinical Immunology, 1971 Eleven asthmatic men were treated with the antimetabolites thioguanosine or 6-mercaptopurine. Eight completed 12 weeks of treatment. Reversible drug toxicity occurred in 2 patients. Four patients with severe chronic asthma, chronic bronchitis, and continuous wheezing were not improved. Five patients with intermittent asthma of recent onset improved and
Tryggvi Asmundsson +3 more
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Immunosuppressive drug therapy
Current Opinion in Rheumatology, 1989Interstitial lung disease frequently complicates rheumatic disorders, especially polymyositis-dermatomyositis, rheumatoid arthritis, systemic sclerosis, and mixed connective tissue disease. In this article, we review the current data supporting the use of azathioprine, cyclophosphamide, chlorambucil, cyclosporine, and methotrexate in the management of ...
W J, McCune, D K, Vallance, J P, Lynch
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Surgical Clinics of North America, 1999
Although several new immunosuppressive medications have been developed in the past decade, many possible avenues are yet to be explored. Although the newer agents have not reflected any clear benefit in patient or graft survival over CsA or tacrolimus, they have been useful in reducing the incidence and severity of rejection, reducing the concomitant ...
John J. Fung +5 more
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Although several new immunosuppressive medications have been developed in the past decade, many possible avenues are yet to be explored. Although the newer agents have not reflected any clear benefit in patient or graft survival over CsA or tacrolimus, they have been useful in reducing the incidence and severity of rejection, reducing the concomitant ...
John J. Fung +5 more
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Immunosuppressive Therapy in Transplantation [PDF]
Nursing Clinics of North America, 2016 This article discusses immunosuppressive medications used in organ and hematopoietic stem cell transplantation. Induction, maintenance, and rescue therapy are administered throughout different periods during and after transplantation to modulate the immune system response in the recipient to prevent or treat rejection or graft-versus-host disease ...
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Update on immunosuppressive therapy
Current Opinion in Rheumatology, 1998In this review we summarize selected articles that have been published about immunosuppressive agents in the past year. These studies fall into three major categories: 1) use of pulse cyclophosphamide in autoimmune diseases other than systemic lupus erythematosus; 2) use of newer immunosuppressive agents such as cyclosporine and FK506 in a variety of ...
W J McCune, N G Singer
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Current Opinion in Immunology, 1992
Although Cyclosporin A has improved transplant outcome, its use has serious limitations due to its narrow therapeutic window. New approaches to broaden this window exploit alternative drug formulations, pharmacokinetic profiling and new immunosuppressive agents, such as Rapamycin and Brequinar, which act in a synergistic fashion.
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Although Cyclosporin A has improved transplant outcome, its use has serious limitations due to its narrow therapeutic window. New approaches to broaden this window exploit alternative drug formulations, pharmacokinetic profiling and new immunosuppressive agents, such as Rapamycin and Brequinar, which act in a synergistic fashion.
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Advances in Immunosuppressive Therapy
Seminars in Respiratory and Critical Care Medicine, 2007Despite the intense interest in biological agents, traditional immunosuppressive drugs remain the mainstays of treatment for systemic rheumatic diseases that involve the lung. Herewith, we review the mechanism of action, administration and clinical use of immunosuppressive drugs, including cyclophosphamide, chlorambucil, azathioprine, methotrexate ...
Wendy Marder, W. Joseph McCune
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Immunosuppressive therapy and the skeleton
Trends in Endocrinology & Metabolism, 1994Glucocorticoids and other immunosuppressive drugs, such as cytoclosporine A, are increasingly used today. One of the most common clinical situations in which they are prescribed is for immunosuppression after organ transplantation. These drugs have diverse effects on the skeleton, however, and one of the most common sequelae of organ transplantation is
S. Epstein, Elizabeth Shane
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Immunosuppressive Therapy for Asthma
Allergy and Asthma Proceedings, 1995Over the last four or five years, there have been some serious attempts to look for alternatives to corticosteroids in the management of severe bronchial asthma. Rheumatologists and dermatologists long ago recognized the importance of replacing corticosteroids with other agents.
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