Results 91 to 100 of about 174,772 (308)
Pharmacokinetics of immunosuppressive agents during hemoperfusion in a sheep model. [PDF]
Front Med (Lausanne), 2023 Leber B +7 more
europepmc +1 more source
Possibilities of Inner Ear Barrier Models for Otologic Drug Development
Advanced Therapeutics, EarlyView.This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn +7 more
wiley +1 more source
Advanced Science, EarlyView.This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma +10 more
wiley +1 more source
IMMUNOSUPPRESSIVE AGENT CYCLOSPORIN A AND VARIOUS CELL GROWTH FACTORS AFFECT CLONED OSTEOBLASTIC CELL LINE MC3T3-E1 CELLS [PDF]
, 1988 K. Okano +11 more
openalex +1 more source
Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
Advanced Science, EarlyView.Neuromyelitis optica spectrum disorder (NMOSD) has distinct acute‐remitting courses but lacks biomarkers for predicting relapse. Recent studies found cuproptosis‐related genes affect its course, and a model built accordingly can predict relapse to aid intervention.
Peidong Liu +17 more
wiley +1 more source
Live attenuated vaccines in patients receiving immunosuppressive agents. [PDF]
Pediatr Nephrol, 2023 Kamei K.
europepmc +1 more source
Advanced Science, EarlyView.Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu +16 more
wiley +1 more source
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. [PDF]
, 1990 Angela Granelli‐Piperno +3 more
openalex +1 more source