Results 111 to 120 of about 202,943 (249)

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

Advanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu, Mengyu Guo, Jun Guan, Xiaofeng He, Mingdi Hu, Fene Gao, Klaus Müllen, Chendong Ji, Chunying Chen, Meizhen Yin   +9 more
wiley   +1 more source

Insights on the role of anti-inflammatory and immunosuppressive agents in the amelioration of diabetes. [PDF]

Diabetol Int, 2023
Rai U, Senapati D, Arora MK.
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Pharmacogenomics of the immunosuppressive agents

Japanese Journal of Clinical Immunology, 2002
Atsuo, Taniguchi, Wako, Urano, Eiichi, Tanaka, Yutaka, Kitamura, Masayuki, Saito, Hideto, Akama, Hishashi, Yamanak, Terunobu, Saito, Naoyuki, Kamatani   +8 more
openaire   +3 more sources

Nanotechnology-based alternatives for the topical delivery of immunosuppressive agents in psoriasis. [PDF]

Int J Pharm, 2023
Gomes GS, Frank LA, Contri RV, Longhi MS, Pohlmann AR, Guterres SS.   +5 more
europepmc   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Bacterial Infections Associated with Immunosuppressive Agents Commonly Used in Patients with Interstitial Lung Diseases. [PDF]

Pathogens, 2023
Chaaban S, Sadikot RT.
europepmc   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Update on Therapy for Non-Infectious Scleritis

Clinical Ophthalmology
Allison Richey,1 Victoria Sattarova,2 Laura J Kopplin,3 Karen R Armbrust1 1Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA; 2Department of Ophthalmology, Hennepin County Medical Center, Minneapolis, MN,
Richey A, Sattarova V, Kopplin LJ, Armbrust KR   +3 more
doaj  

Immunogenicity and safety of SARS-CoV-2 vaccine with immunosuppressive agents. [PDF]

Pediatr Int, 2022
Kamei K, Ogura M, Sato M, Nishi K, Shoji K, Funaki T, Ogimi C, Ito S.   +7 more
europepmc   +1 more source