Results 151 to 160 of about 560,370 (324)

Immunotherapy

Canadian Family Physician, 2021
openaire   +2 more sources

Complete remissions following immunotherapy or immuno-oncology combinations in cancer patients: the MOUSEION-03 meta-analysis

Cancer Immunology and Immunotherapy, 2023
M. Santoni, Alessandro Rizzo, J. Kucharz, V. Mollica, M. Rosellini, Andrea Marchetti, Elisa Tassinari, F. Monteiro, A. Soares, J. Molina-Cerrillo, E. Grande, N. Battelli, F. Massari   +12 more
semanticscholar   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Stereotactic radiotherapy for metastatic brain tumors: A comparative analysis of dose distributions among VMAT, Helical TomoTherapy, CyberKnife, Gamma Knife, and ZAP‐X

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract This study evaluates various radiotherapy techniques for treating metastatic brain tumor (BT), focusing on non‐coplanar volumetric modulated arc radiotherapy (NC‐VMAT), coplanar VMAT (C‐VMAT), Helical TomoTherapy (HT), CyberKnife (CK), Gamma Knife (GK), and ZAP‐X.
Toshihiro Suzuki, Masahide Saito, Ryutaro Nomura, Hikaru Nemoto, Naoto Yanagisawa, Ryuma Sawada, Zennosuke Mochizuki, Naoki Sano, Hiroshi Onishi, Hiroshi Takahashi   +9 more
wiley   +1 more source

Multimodal Integration of Longitudinal Noninvasive Diagnostics for Survival Prediction in Immunotherapy Using Deep Learning [PDF]

arXiv
Purpose: Analyzing noninvasive longitudinal and multimodal data using artificial intelligence could potentially transform immunotherapy for cancer patients, paving the way towards precision medicine. Methods: In this study, we integrated pre- and on-treatment blood measurements, prescribed medications and CT-based volumes of organs from a large pan ...
arxiv  

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar, Taindra Neupane, Lydia Wilson, Jennifer Kwak, Richard Castillo, Edward Castillo, Yevgeniy Vinogradskiy   +6 more
wiley   +1 more source

Phase I/II Clinical Study of PRaG Regimen Combined With Intraperitoneal Infusion of PD-1 Inhibitor for Advanced Refractory Solid Tumors With Cancerous Ascites (PRaG4.0P Study)

Technology in Cancer Research & Treatment
Objective: The prognosis of malignant tumors with peritoneal metastases and cancerous ascites has generally been poor, with limited treatment options.
Yingying Xu MS, Yuehong Kong MS, Yifu Ma MS, Meiling Xu MS, Jiabao Yang MS, Junjun Zhang PhD, Rongzheng Chen MS, Guangqiang Chen MS, Zhihui Hong MS, Xiangrong Zhao MS, Chenyang Zhang MS, Pengfei Xing MS, Liyuan Zhang MD, Peifeng Zhao MS   +13 more
doaj   +1 more source

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Nature Network Boston, 2018
Peng Jiang, Shengqing Gu, D. Pan, Jingxin Fu, A. Sahu, Xihao Hu, Ziyi Li, Nicole Traugh, Xia Bu, Bo Li, Bo Li, Jun Liu, G. Freeman, Myles A. Brown, K. Wucherpfennig, X. Liu   +15 more
semanticscholar   +1 more source

B cells and tertiary lymphoid structures promote immunotherapy response

Nature, 2020
Beth A. Helmink, S. Reddy, Jianjun Gao, Shaojun Zhang, R. Başar, R. Thakur, Keren Yizhak, Moshe Sade-Feldman, J. Blando, Guangchun Han, V. Gopalakrishnan, Y. Xi, Hao Zhao, R. Amaria, H. Tawbi, Alexandria P. Cogdill, Wenbin Liu, Valerie S. LeBleu, Fernanda G. Kugeratski, S. Patel, M. Davies, P. Hwu, Jeffrey E. Lee, J. Gershenwald, A. Lucci, R. Arora, S. Woodman, E. Keung, P. Gaudreau, A. Reuben, C. Spencer, E. Burton, L. Haydu, A. Lazar, Roberta Zapassodi, C. Hudgens, D. Ledesma, Sufey Ong, M. Bailey, S. Warren, Disha Rao, O. Krijgsman, E. Rozeman, D. Peeper, C. Blank, T. Schumacher, L. Butterfield, M. Zelazowska, Kevin M. McBride, R. Kalluri, J. Allison, F. Petitprez, W. Fridman, C. Sautès-Fridman, N. Hacohen, K. Rezvani, Padmanee Sharma, M. Tetzlaff, Linghua Wang, J. Wargo   +59 more
semanticscholar   +1 more source