Results 161 to 170 of about 560,370 (324)

Vaccines and Immunotherapy

, 2014
This chapter examines the general topic of vaccines. The goal is to develop a perspective on active and passive immunization for vaccination against infectious agents of multiple classes. A discussion also will demonstrate how principles in immunology combine with biotechnology to advance the field of vaccinology.
openaire   +1 more source

IMMUNOTHERAPY

HemaSphere, 2022
openaire   +2 more sources

The blockade of immune checkpoints in cancer immunotherapy

Nature Reviews. Cancer, 2012
D. Pardoll
semanticscholar   +1 more source

CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh, Yoonhyuk Jang, Soo Jean Shin, Soo Hyun Ahn, Su Yee Mon, Yoon Hee Shin, Kon Chu, Sang Kun Lee, Soon‐Tae Lee   +8 more
wiley   +1 more source

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Cell, 2017
Padmanee Sharma, S. Hu-Lieskovan, J. Wargo, A. Ribas   +3 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Nature Genetics, 2019
R. Samstein, Chung-Han Lee, A. Shoushtari, M. Hellmann, R. Shen, Y. Janjigian, D. Barron, A. Zehir, E. Jordan, A. Omuro, T. Kaley, S. Kendall, R. Motzer, A. Hakimi, M. Voss, P. Russo, J. Rosenberg, G. Iyer, B. Bochner, D. Bajorin, H. Al-Ahmadie, J. Chaft, C. Rudin, Gregory Riely, S. Baxi, A. Ho, R. Wong, D. Pfister, J. Wolchok, C. Barker, P. Gutin, C. Brennan, V. Tabar, I. Mellinghoff, L. Deangelis, C. Ariyan, N. Lee, W. Tap, M. Gounder, S. D’Angelo, L. Saltz, Z. Stadler, H. Scher, J. Baselga, P. Razavi, C. Klebanoff, R. Yaeger, N. Segal, G. Ku, R. DeMatteo, M. Ladanyi, N. Rizvi, M. Berger, N. Riaz, D. Solit, T. Chan, L. Morris   +56 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

PLK1 phosphorylates RhoGDI1 and promotes cancer cell migration and invasion

Cancer Cell International
Background Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays an important role in diverse cellular processes by regulating Rho guanosine triphosphate (GTP)ases activity. RhoGDI1 phosphorylation regulates the spatiotemporal activation of Rho
Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho, Hee Gu Lee   +7 more
doaj   +1 more source

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

Advanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang, Xin Zhang, Denghui Xie, Chunying Chen, Zhifeng Huang, Zhong Alan Li   +5 more
wiley   +1 more source