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Mechanisms of Aeroallergen Immunotherapy: Subcutaneous Immunotherapy and Sublingual Immunotherapy.
Immunology and allergy clinics of North America, 2016Allergen immunotherapy (AIT) is an effective way to treat allergic disorders, targeting the underlying mechanisms and altering the disease course by inducing a long-lasting clinical and immune tolerance to allergens. Although sublingual and subcutaneous routes are used in daily practice, many novel ways to decrease side effects and duration and ...
Ozdemir, Cevdet +3 more
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Journal of Allergy and Clinical Immunology, 2001
Recent claims have been made that sublingual immunotherapy (SLIT) may be a viable alternative to injection immunotherapy (SIT). Animal studies show that when allergens are administered topically, they are handled differently, and IgE responses can be reduced.
Frew, Anthony J., Smith, Helen E.
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Recent claims have been made that sublingual immunotherapy (SLIT) may be a viable alternative to injection immunotherapy (SIT). Animal studies show that when allergens are administered topically, they are handled differently, and IgE responses can be reduced.
Frew, Anthony J., Smith, Helen E.
openaire +3 more sources
Immunology
Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be disappointing. Recent studies have shed light on how not just tumour cells, but also the complex tumour microenvironment, contribute to this unfavourable outcome of ...
Zhibin Wang +6 more
semanticscholar +1 more source
Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be disappointing. Recent studies have shed light on how not just tumour cells, but also the complex tumour microenvironment, contribute to this unfavourable outcome of ...
Zhibin Wang +6 more
semanticscholar +1 more source
Surgical Oncology Clinics of North America, 2019
Oncolytic viruses are naturally occurring, or genetically engineered viruses that can be administered via intralesional injections or intravenously to induce cell death in tumor cells and activate antitumor immune responses. This review summarizes several oncolytic viruses in preclinical and clinical trials, describes challenges in clinical ...
Morgan L, Hennessy +3 more
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Oncolytic viruses are naturally occurring, or genetically engineered viruses that can be administered via intralesional injections or intravenously to induce cell death in tumor cells and activate antitumor immune responses. This review summarizes several oncolytic viruses in preclinical and clinical trials, describes challenges in clinical ...
Morgan L, Hennessy +3 more
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2016
Gliomas are the most common primary brain tumors of the central nervous system, and carry a grim prognosis. Novel approaches utilizing the immune system as adjuvant therapy are quickly emerging as viable and effective options. Immunotherapeutic strategies being investigated to treat glioblastoma include: vaccination therapy targeted against either ...
Brandon D, Liebelt +2 more
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Gliomas are the most common primary brain tumors of the central nervous system, and carry a grim prognosis. Novel approaches utilizing the immune system as adjuvant therapy are quickly emerging as viable and effective options. Immunotherapeutic strategies being investigated to treat glioblastoma include: vaccination therapy targeted against either ...
Brandon D, Liebelt +2 more
openaire +2 more sources
Seminars in Oncology, 2014
Radiation therapy and immunotherapy are both well-established treatments for malignant disease. Radiotherapy has long been utilized for purposes of providing local tumor control, and the recent success with novel immunomodulatory agents has brought immunotherapy into the forefront of clinical practice for the treatment of many tumor types.
Susan M, Hiniker, Susan J, Knox
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Radiation therapy and immunotherapy are both well-established treatments for malignant disease. Radiotherapy has long been utilized for purposes of providing local tumor control, and the recent success with novel immunomodulatory agents has brought immunotherapy into the forefront of clinical practice for the treatment of many tumor types.
Susan M, Hiniker, Susan J, Knox
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Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
Science, 2018B. Routy +47 more
semanticscholar +1 more source
USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy
Proceedings of the National Academy of Sciences of the United States of AmericaSignificance Ferroptosis is pivotal in various physiological and pathological processes, yet our understanding of its mechanisms and implications for tissue homeostasis and cancer immunotherapy remains incomplete.
Haiou Li +16 more
semanticscholar +1 more source
Veterinary Clinics of North America: Small Animal Practice, 2019
The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
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The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
openaire +2 more sources
Neoantigens in cancer immunotherapy
Science, 2015T. Schumacher, R. Schreiber
semanticscholar +1 more source