Results 31 to 40 of about 314,880 (255)
, 2016 Purpose: IMP researchers have shown interest in how innovations result from interaction among companies, while, and in parallel, there has been an increased focus on open innovation (OI) during the past decade.
Öberg, Christina,
core +1 more source
IMP-1088 reduces EV infectivity without directly affecting yield.
, 2022 (A) Schematic representation of assays used to assess VACV EV production after treatment with IMP-1088. (B) BSC-40 cells were infected with VACV IHD-J in presence of inhibitors 40 μg/mL AraC, 2 μM ST-246 and 2 μM IMP-1088 for 24 h.
Catherine A. Cotter (13933347) +10 more
core +1 more source
salilab/imp: IMP 2.11.1 release
, 2019 <p>This is a bugfix release, which fixes some issues with the build system, failures to read RMF files, and cloning of molecular hierarchies. See the <a href="https://integrativemodeling.org/2.11.1/doc/manual/changelog.html">full change log ...
Thomas-Otavio Peulen +15 more
core +1 more source
ACTRIS IMP D7.1: Recommendations for optimizing the access process and user interaction
, 2022 ACTRIS is a large, highly distributed pan-European Research Infrastructure that has entered its implementation phase in 2020. The aim of the ACTRIS Implementation project (ACTRIS IMP) is to coordinate and accomplish the actions required for implementing ...
Dubost, Ariane, Philippin, Sabine
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in Neural Circuits, 2021 Opposite emotions like fear and reward states often utilize the same brain regions. The bed nucleus of the stria terminalis (BNST) comprises one hub for processing fear and reward processes.
Nadia Kaouane +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Efficient labeling of french mammogram reports with MammoBERT
Scientific ReportsRecent advances in deep learning and natural language processing (NLP) have broadened opportunities for automatic text processing in the medical field.
Nazanin Dehghani +5 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source