Results 141 to 150 of about 30,396,780 (392)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Impact of Impact

Hypothesis, 2008
This spawned a debate in the lab; how important is a journal’s impact factor, anyway? In this age of on-line journals and internet publication searches, is a particular paper really more likely to be seen by others (ie. have more impact) by being published in one particular journal rather than another? Surely, an important result will be seen by anyone
openaire   +1 more source

US publisher moves to make catalogue of over 4,000 academic texts available free online [PDF]

, 2011
In a new move to make academic content more accessible to a wider audience across the globe, the National Academies Press announced this month that PDF versions of all its books will be available for download to anyone across the globe free of charge ...
Impact of Social Sciences Blog, at LSE
core  

The effects of agricultural output market access interventions on agricultural, socio‐economic, food security, and nutrition outcomes in low‐ and middle‐income countries: A systematic review

Campbell Systematic Reviews
Background An estimated two billion people do not have sufficient access to nutritious food, and nearly half are dependent on small‐scale and subsistence farming.
Pierre Marion, Etienne Lwamba, Andrea Floridi, Suvarna Pande, Megha Bhattacharyya, Sarah Young, Paul Fenton Villar, Shannon Shisler   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Degradation and sorption of the herbicide pelargonic acid in subsoils below railway tracks compared to a range of topsoils

Environmental Sciences Europe
Background Pelargonic acid is a non-selective herbicide derived from natural sources with a range of potential applications in areas where synthetic herbicides may be less acceptable. One such use area is weed control on railway tracks.
Thomas Poiger, Joanna Müller, Roy Kasteel, Ignaz J. Buerge   +3 more
doaj   +1 more source

The formation, properties and impact of secondary organic aerosol: current and emerging issues

, 2009
Secondary organic aerosol (SOA) accounts for a significant fraction of ambient tropospheric aerosol and a detailed knowledge of the formation, properties and transformation of SOA is therefore required to evaluate its impact on atmospheric processes ...
M. Hallquist, J. Wenger, U. Baltensperger, Y. Rudich, D. Simpson, M. Claeys, J. Dommen, N. Donahue, C. George, A. Goldstein, J. Hamilton, H. Herrmann, T. Hoffmann, Y. Iinuma, M. Jang, M. Jenkin, J. Jimenez, A. Kiendler‐Scharr, W. Maenhaut, G. Mcfiggans, T. Mentel, A. Monod, A. Prévôt, J. Seinfeld, J. Surratt, R. Szmigielski, J. Wildt   +26 more
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source