Results 161 to 170 of about 13,555,111 (308)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

New lunar crater reveals extensive distal regolith modification. [PDF]

Sci Adv
Powell TM, Greenhagen BT, Horvath T, Williams JP, Jhoti E, Speyerer EJ, Elder CM, Paige DA.   +7 more
europepmc   +1 more source

Epidemiological changes in breast tumours in Italy: the IMPACT study on mammographic screening programmes

, 2011
No abstract ...
IMPACT WORKING Group, FERRETTI, Stefano
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Review of impact assessments on women's economic empowerment and technology adoption

This report reviews impact assessments undertaken across the CGIAR portfolio. Impact assessments at CGIAR provide empirical evidence to help policymakers, researchers and stakeholders make informed decisions about which agricultural technologies and ...
CGIAR GENDER Impact Platform
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Psychometric Evaluation of the HIV Knowledge Questionnaire-18 in a Black Canadian Population

HIV/AIDS: Research and Palliative Care
Agatha Nyambi,1 Elizabeth Alvarez,1 Laura N Anderson,1 Fatimah Jackson-Best,1 Wangari Tharao,2 Egbe B Etowa,3 Shamara Baidoobonso,4 Maureen Owino,5 Pascal Djiadeu,1 Daeria O Lawson,1 Lawrence Mbuagbaw1,6– 10 1Department of Health Research Methods ...
Nyambi A, Alvarez E, Anderson LN, Jackson-Best F, Tharao W, Etowa EB, Baidoobonso S, Owino M, Djiadeu P, Lawson DO, Mbuagbaw L   +10 more
doaj  

The Effect of Head-Forward Posture on Lower Neck Loads and Dislocation Risk in Head-First Impact: A Computational and Experimental Investigation. [PDF]

JOR Spine
Mongiardini M, Cronin D, Quarrington RD.
europepmc   +1 more source

On impact [PDF]

Nature Methods, 2015
openaire   +2 more sources

Impact Connector

, 2018
In this newsletter we articulate some of the principles, practices, achievements and questions surrounding Indigenous impact assessment (Cultural Impact Assessment).
Jolly, Dyanna
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