Results 171 to 180 of about 10,862,053 (317)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of response shift on change in patient-reported outcomes: a systematic review. [PDF]

open access: yesQual Life Res
Verdam MGE   +5 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CGIAR Climate Impact Area Webinar Series - Webinar 1: How can attribution science inform loss and damage? [PDF]

open access: yes
As the climate changes, extreme weather events’ frequency and intensity increase. Record-breaking heat waves on land and in the ocean, drenching rains, severe floods, years-long droughts, extreme wildfires, and widespread flooding are all becoming more ...
CGIAR Climate Change Impact Platform
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Psychometric Evaluation of the HIV Knowledge Questionnaire-18 in a Black Canadian Population

open access: yesHIV/AIDS: Research and Palliative Care
Agatha Nyambi,1 Elizabeth Alvarez,1 Laura N Anderson,1 Fatimah Jackson-Best,1 Wangari Tharao,2 Egbe B Etowa,3 Shamara Baidoobonso,4 Maureen Owino,5 Pascal Djiadeu,1 Daeria O Lawson,1 Lawrence Mbuagbaw1,6– 10 1Department of Health Research Methods ...
Nyambi A   +10 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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