Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Impact of response shift on change in patient-reported outcomes: a systematic review. [PDF]
Verdam MGE +5 more
europepmc +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
CGIAR Climate Impact Area Webinar Series - Webinar 1: How can attribution science inform loss and damage? [PDF]
As the climate changes, extreme weather events’ frequency and intensity increase. Record-breaking heat waves on land and in the ocean, drenching rains, severe floods, years-long droughts, extreme wildfires, and widespread flooding are all becoming more ...
CGIAR Climate Change Impact Platform
core
Academic Philanthropy to Improve the Impact Factor of Journals Published from Developing Countries. [PDF]
Saxena A, Keshava SN, Sureka B.
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Psychometric Evaluation of the HIV Knowledge Questionnaire-18 in a Black Canadian Population
Agatha Nyambi,1 Elizabeth Alvarez,1 Laura N Anderson,1 Fatimah Jackson-Best,1 Wangari Tharao,2 Egbe B Etowa,3 Shamara Baidoobonso,4 Maureen Owino,5 Pascal Djiadeu,1 Daeria O Lawson,1 Lawrence Mbuagbaw1,6– 10 1Department of Health Research Methods ...
Nyambi A +10 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Energy transfer mechanism in ultrasonic impact and its single-cycle equivalent experimental methodology. [PDF]
Jiang Q +6 more
europepmc +1 more source

