Results 41 to 50 of about 7,146,949 (298)

Modeling surge dynamics improves coastal flood estimates in a global set of tropical cyclones

open access: yesCommunications Earth & Environment
Tropical cyclone-induced storm surge is a major coastal risk, which will be further amplified by rising sea levels under global warming. Here, we present a computational efficient, globally applicable modeling approach in which ocean surge and coastal ...
Thomas Vogt   +4 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

To impact or not to impact, this is not a question for BioImpacts! [PDF]

open access: yesBioImpacts, 2017
BioImpacts was launched in March 2011 as a peer-reviewed, open-access journal. Now it is the leading scientific journal of Tabriz University of Medical Sciences (TUOMS) targeting the international scientific community. With several excellent review and research papers published in recent issues, it has secured a reputable status among similar journals ...
openaire   +3 more sources

Analyzing the usage of theories of change for routine immunization programs -- a review of impact evaluations from LMICs

open access: yesJournal of Health, Population and Nutrition
Background In this article we analyzed the extent of the usage of Theories of Change (TOCs) and causal pathways in the evaluation of immunization programs to identify the challenges to generating evidence on how interventions improve immunization ...
Lalitha Vadrevu   +2 more
doaj   +1 more source

Genetic variation in individuals from a population of the minimalist bacteriophage Merri-merri-uth nyilam marra-natj driving evolution of the virus

open access: yesmBio
In a survey of a waterway on Wurundjeri land, two sub-populations of the bacteriophage Merri-merri-uth nyilam marra-natj (phage MMNM) were isolated on a permissive host, Klebsiella B5055 of capsule-type K2, but were distinguished by minor phenotypic ...
Tze Y. Thung   +10 more
doaj   +1 more source

Staying safe while staying together: the COVID‐19 paradox for participants returning to community‐based sport in Victoria, Australia

open access: yesAustralian and New Zealand Journal of Public Health, 2021
Objective: To identify the challenges adult community sport participants anticipate when returning to sport in Victoria, Australia, post a COVID‐19 shutdown.
Kiera Staley   +7 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Chinese Impacts and Impacting China [PDF]

open access: yesJournal of Current Chinese Affairs, 2013
Introduction to Journal of Current Chinese Affairs 1/2013: Chinese Impacts and Impacting China.
openaire   +4 more sources

Ambient forcing: sampling local perturbations in constrained phase spaces

open access: yesNew Journal of Physics, 2022
Ambient forcing is a novel method to sample random states from manifolds of differential-algebraic equations (DAE). These states can represent local perturbations of nodes in power systems with loads, which introduces constraints into the system.
Anna Büttner   +2 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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