Results 91 to 100 of about 13,192,083 (308)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A Racial Impact Analysis of HB 936: Accessibility of Electronic Textbooks [PDF]
, 2014 The economic and social consequences of the lack of access to technology for students in the Commonwealth of Virginia are real and significant. This report provides a legislative racial impact analysis of House Bill (HB) 936, a proposed bill in the ...
Avery, Melanie +4 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Extreme weather events in early summer 2018 connected by a recurrent hemispheric wave-7 pattern
Environmental Research Letters, 2019 The summer of 2018 witnessed a number of extreme weather events such as heatwaves in North America, Western Europe and the Caspian Sea region, and rainfall extremes in South-East Europe and Japan that occurred near-simultaneously.
Kai Kornhuber +6 more
doaj +1 more source
Analysis of simple 2-D and 3-D metal structures subjected to fragment impact [PDF]
, 1977 Theoretical methods were developed for predicting the large-deflection elastic-plastic transient structural responses of metal containment or deflector (C/D) structures to cope with rotor burst fragment impact attack.
Rodal, J. J. A. +3 more
core +1 more source
Droplet impact on water layers: post-impact analysis and computations [PDF]
, 2005 An inviscid model of droplet impact into a water layer is examined analytically for small times just after impact and computationally for order-one distortion times. Various layer depths are considered, as are surface-tension effects. Good correspondence
Purvis, R., Smith, F.T.
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Impact Analysis of Microfinance in Nigeria [PDF]
, 2011 This paper applies the financing constraints approach to study whether microfinance institutions improved access to credit for microenterprises in Nigeria or not.
Babajide, Abiola
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