Results 51 to 60 of about 1,599,471 (300)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Effect of Impact Angle on Particle Fracture Phenomenon

open access: yesAerosol and Air Quality Research, 2022
The effect of terephthalic acid particle properties on particle fracture phenomena was investigated in this study. Furthermore, to evaluate the fracture characteristics in real process, the effect of the particle impact angle on particle fracture ...
Hiroshi Satone   +2 more
doaj   +1 more source

Impact of the diaphyseal femoral deformity on the lower limb alignment in osteoarthritic varus knees

open access: yesBone & Joint Open, 2023
Aims: The impact of a diaphyseal femoral deformity on knee alignment varies according to its severity and localization. The aims of this study were to determine a method of assessing the impact of diaphyseal femoral deformities on knee alignment for the ...
Cécile Batailler   +5 more
doaj   +1 more source

Generalized Formulation of Weighted Optimal Guidance Laws with Impact Angle Constraint

open access: yes, 2013
The purpose of this paper is to investigate the generalized formulation of weighted optimal guidance laws with impact angle constraint. From the generalized formulation, we explicitly find the feasible set of weighting functions that lead to analytical ...
Lee, Chang-Hun   +2 more
core   +1 more source

Impact of basic angle variations on the parallax zero point for a scanning astrometric satellite [PDF]

open access: yes, 2017
Determination of absolute parallaxes by means of a scanning astrometric satellite such as Hipparcos or Gaia relies on the short-term stability of the so-called basic angle between the two viewing directions. Uncalibrated variations of the basic angle may
Butkevich, Alexey G.   +4 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

New Insights into the Estimation of Impact Load of Granular Flow against a Rigid Wall

open access: yesShock and Vibration, 2022
The installation of a rigid wall is a main approach to mitigate a granular flow. The methods of the impact load against a rigid wall still remains a challenge.
Xiao Siyou, Yang Junwei, Wei Zhongju
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Structure determination from powder data : Mogul and CASTEP [PDF]

open access: yes, 2009
When solving the crystal structure of complex molecules from powder data, accurately locating the global minimum can be challenging, particularly where the number of internal degrees of freedom is large.
Bardin, J.   +5 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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