Results 81 to 90 of about 214,638 (308)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Electron Impact Ionization of Lithium

, 1982
The electron impact ionization cross section of the neutral lithium atom has been calculated in a distorted wave exchange approximation. The total cross section is in good agreement with available experimental data at incident electron energies above 10 ...
Younger, S.M.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Seize the Moments: Approximating American Option Prices in the GARCH Framework [PDF]

This paper proposes an efficient approach to compute the prices of American style options in the GARCH framework. Rubinstein's (1998) Edgeworth tree idea is combined with the analytical formulas for moments of the cumulative return under GARCH developed ...
Caroline Sasseville, Genevieve Gauthier, Jin-Chuan Duan, Jean-Guy Simonato   +3 more
core  

On the impact of the mixed Z/γ PDF at muon colliders

Journal of High Energy Physics
We study the role of the Z/γ-interference parton distribution function (PDF) in high-energy muon colliders. We review how this PDF emerges when electroweak interactions are applied to the collinear splitting process and show that the leading-order ...
David Marzocca, Alfredo Stanzione
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Impact of the Scalar Approximation on the Prediction of the Group Velocity Dispersion

, 2011
A detailed study of the impact of using a scalar approximation to the wave equation on the prediction of the group velocity dispersion is shown by comparing predictions against results obtained by using a full-vectorial wave equation and measurements of ...
Gruner-Nielsen, L., Poul Kristensen, Lars Gruner-Nielsen, Rottwitt, Karsten, Martin Erland Vestergaard Pedersen, Karsten Rottwitt, Pedersen, Martin Erland Vestergaard, Kristensen, P.   +7 more
core   +1 more source

Undulator radiation brightness and coherence near the diffraction limit

Physical Review Accelerators and Beams, 2019
The brightness and transverse coherence of undulator radiation in synchrotron light sources is investigated using the Wigner formulation in a full 4D treatment. New results are presented on the impact of energy spread on the brightness and coherence as a
Richard P. Walker
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source